LncRNA-mediated regulation of cell signaling in cancer

WX Peng, P Koirala, YY Mo - Oncogene, 2017 - nature.com
To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered
through functional genomics studies. Importantly, lncRNAs have been shown, in many …

Colorectal carcinoma: a general overview and future perspectives in colorectal cancer

I Mármol, C Sánchez-de-Diego… - International journal of …, 2017 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …

Histone deacetylase inhibitors as anticancer drugs

T Eckschlager, J Plch, M Stiborova… - International journal of …, 2017 - mdpi.com
Carcinogenesis cannot be explained only by genetic alterations, but also involves
epigenetic processes. Modification of histones by acetylation plays a key role in epigenetic …

[HTML][HTML] Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling

M Entezari, M Ghanbarirad, A Taheriazam… - Biomedicine & …, 2022 - Elsevier
Among the different kinds of tumors threatening human life, lung cancer is one that is
commonly observed in both males and females. The aggressive behavior of lung cancer …

The epithelial–mesenchymal transition at the crossroads between metabolism and tumor progression

M Fedele, R Sgarra, S Battista, L Cerchia… - International journal of …, 2022 - mdpi.com
The transition between epithelial and mesenchymal phenotype is emerging as a key
determinant of tumor cell invasion and metastasis. It is a plastic process in which epithelial …

ncRNA-encoded peptides or proteins and cancer

J Wang, S Zhu, N Meng, Y He, R Lu, GR Yan - Molecular Therapy, 2019 - cell.com
Non-coding RNAs (ncRNAs) are unique RNA transcripts that have been widely identified in
the eukaryotic genome and have been shown to play key roles in the development of many …

The Landscape of long noncoding RNA classification

GS Laurent, C Wahlestedt, P Kapranov - Trends in genetics, 2015 - cell.com
Advances in the depth and quality of transcriptome sequencing have revealed many new
classes of long noncoding RNAs (lncRNAs). lncRNA classification has mushroomed to …

Engineered exosome as targeted lncRNA MEG3 delivery vehicles for osteosarcoma therapy

X Huang, W Wu, D Jing, L Yang, H Guo, L Wang… - Journal of Controlled …, 2022 - Elsevier
Exosomes as nanosized membrane vesicles, could targeted deliver therapeutic agents by
modification with target ligands. Exosome-derived non-coding RNAs play a vital role in the …

Importance of probiotics in the prevention and treatment of colorectal cancer

M Eslami, B Yousefi, P Kokhaei… - Journal of cellular …, 2019 - Wiley Online Library
Colorectal cancer (CRC) remains one of the most common and deadly cancers. Intestinal
gut microflora is important to maintain and contributes to several intestinal functions …

Long noncoding RNAs as biomarkers in cancer

L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …