Exploring the Causality Between Plasma Brain-Derived Neurotrophic Factor and Neurological Diseases: A Mendelian Randomization Study

S Chen, W Huang, T He, M Zhang, X Jin… - Journal of …, 2023 - content.iospress.com
Background: Brain-derived neurotrophic factor (BDNF) is a protein synthesized in the brain
and widely expressed in the nervous system. Previous studies have demonstrated a …

Neuronal activation affects the organization and protein composition of the nuclear speckles

AA Szczepankiewicz, K Parobczak, M Zaręba-Kozioł… - bioRxiv, 2024 - biorxiv.org
Nuclear speckles, also known as interchromatin granule clusters (IGCs), are subnuclear
domains highly enriched in proteins involved in transcription and mRNA metabolism and …

A novel enhancer that regulates Bdnf expression in developing neurons

E Brookes, HY Alan Au, W Varsally, C Barrington… - bioRxiv, 2021 - biorxiv.org
Brain derived neurotrophic factor (BDNF) is a critical secreted peptide that promotes
neuronal differentiation and survival, and its downregulation is implicated in many …

Architektura świadomości. Część II: Struktura molekularna i biofizyka pamięci

WL Galus - Roczniki Filozoficzne, 2015 - ceeol.com
Fundamentem kompleksowego modelu mózgu i wytwarzanego przezeń umysłu muszą być
procesy biofizyczne, biochemiczne, neuronowe i psychiczne, których skoordynowane …

Nuclear Architecture in the Nervous System

K Ito, T Takizawa - Nuclear, Chromosomal, and Genomic Architecture in …, 2022 - Springer
Neurons and glial cells in the nervous system exhibit different gene expression programs for
neural development and function. These programs are controlled by the epigenetic …

Architektura świadomości. Część III: Wola i sens istnienia

W Galus - Roczniki Filozoficzne, 2015 - ceeol.com
W znanym kognitywistycznym dowcipie twórca samo wiadomego robota relacjonuje
pierwszy kontakt z inteligentn maszyn:„powiedziaáa, e mo e my leü, ale na razie podj áa …

O molekularnej patogenezie stresu i depresji

K Pels - Kosmos, 2020 - kosmos.ptpk.org
Patogeneza depresji jest wciąż słabo poznana. Badania naukowe postulują, że istotną rolę
pełnią nieprawidłowości w przekaźnictwie serotonergicznym, na co wskazuje skuteczność …

[PDF][PDF] WJD

WR Lin, KH Liu, TC Ling, MC Wang, WH Lin, SY Zheng… - Diabetes, 2022 - researchgate.net
Diabetic kidney disease (DKD) is one of the major chronic complications of diabetes mellitus
(DM), as well as a main cause of end-stage renal disease. Over the last few years …

Epigenetic regulations in neurological disorders

P Mondal, S Sarkar, A Das - Epigenetics in Organ Specific Disorders, 2023 - Elsevier
Our nervous system, especially the brain is arguably the most complex, specialized and also
most finely tuned organ of our body, controlling major fundamental and advanced functions …

[PDF][PDF] WJD

SY Zheng, XX Wan, PA Kambey, Y Luo, XM Hu, YF Liu… - 2023 - researchgate.net
Wounds in diabetic patients, especially diabetic foot ulcers, are more difficult to heal
compared with normal wounds and can easily deteriorate, leading to amputation. Common …