Artificial intelligence in histopathology: enhancing cancer research and clinical oncology

A Shmatko, N Ghaffari Laleh, M Gerstung, JN Kather - Nature cancer, 2022 - nature.com
Artificial intelligence (AI) methods have multiplied our capabilities to extract quantitative
information from digital histopathology images. AI is expected to reduce workload for human …

Harnessing multimodal data integration to advance precision oncology

KM Boehm, P Khosravi, R Vanguri, J Gao… - Nature Reviews …, 2022 - nature.com
Advances in quantitative biomarker development have accelerated new forms of data-driven
insights for patients with cancer. However, most approaches are limited to a single mode of …

Transformer-based unsupervised contrastive learning for histopathological image classification

X Wang, S Yang, J Zhang, M Wang, J Zhang… - Medical image …, 2022 - Elsevier
A large-scale and well-annotated dataset is a key factor for the success of deep learning in
medical image analysis. However, assembling such large annotations is very challenging …

Deep learning in histopathology: the path to the clinic

J Van der Laak, G Litjens, F Ciompi - Nature medicine, 2021 - nature.com
Abstract Machine learning techniques have great potential to improve medical diagnostics,
offering ways to improve accuracy, reproducibility and speed, and to ease workloads for …

Transmil: Transformer based correlated multiple instance learning for whole slide image classification

Z Shao, H Bian, Y Chen, Y Wang… - Advances in neural …, 2021 - proceedings.neurips.cc
Multiple instance learning (MIL) is a powerful tool to solve the weakly supervised
classification in whole slide image (WSI) based pathology diagnosis. However, the current …

[HTML][HTML] Deep learning-enabled medical computer vision

A Esteva, K Chou, S Yeung, N Naik, A Madani… - NPJ digital …, 2021 - nature.com
A decade of unprecedented progress in artificial intelligence (AI) has demonstrated the
potential for many fields—including medicine—to benefit from the insights that AI techniques …

[HTML][HTML] Digital pathology and artificial intelligence in translational medicine and clinical practice

V Baxi, R Edwards, M Montalto, S Saha - Modern Pathology, 2022 - Elsevier
Traditional pathology approaches have played an integral role in the delivery of diagnosis,
semi-quantitative or qualitative assessment of protein expression, and classification of …

[HTML][HTML] Review of deep learning: concepts, CNN architectures, challenges, applications, future directions

L Alzubaidi, J Zhang, AJ Humaidi, A Al-Dujaili… - Journal of big Data, 2021 - Springer
In the last few years, the deep learning (DL) computing paradigm has been deemed the
Gold Standard in the machine learning (ML) community. Moreover, it has gradually become …

Pan-cancer image-based detection of clinically actionable genetic alterations

JN Kather, LR Heij, HI Grabsch, C Loeffler, A Echle… - Nature cancer, 2020 - nature.com
Molecular alterations in cancer can cause phenotypic changes in tumor cells and their
microenvironment. Routine histopathology tissue slides, which are ubiquitously available …

GasHis-Transformer: A multi-scale visual transformer approach for gastric histopathological image detection

H Chen, C Li, G Wang, X Li, MM Rahaman, H Sun… - Pattern Recognition, 2022 - Elsevier
In this paper, a multi-scale visual transformer model, referred as GasHis-Transformer, is
proposed for Gastric Histopathological Image Detection (GHID), which enables the …