[HTML][HTML] Strategies to mitigate and treat orthopaedic device-associated infections

DG Kennedy, AM O'Mahony, EP Culligan… - Antibiotics, 2022 - mdpi.com
Orthopaedic device implants play a crucial role in restoring functionality to patients suffering
from debilitating musculoskeletal diseases or to those who have experienced traumatic …

Physicochemical, osteogenic and antimicrobial properties of graphene oxide reinforced silver/strontium-doped hydroxyapatite on titanium for potential orthopedic …

Y Huang, Y Zhang, M Li, H Yang, J Liang… - Surface and Coatings …, 2022 - Elsevier
Variety of ion-doped apatite coatings, especially strontium substituted hydroxyapatite
(SrHA), have attracted eventful attention for medical metal surface modifications due to their …

[HTML][HTML] Antimicrobial activity of ion-substituted calcium phosphates: A systematic review

R Kamphof, RNO Lima, JW Schoones, JJ Arts… - Heliyon, 2023 - cell.com
In this systematic review, the antimicrobial effect of ion-substituted calcium phosphate
biomaterials was quantitatively assessed. The literature was systematically searched up to …

A study on biological properties of titanium implants coated with multisubstituted hydroxyapatite

MV Khvostov, NV Bulina, NA Zhukova… - Ceramics …, 2022 - Elsevier
In this work, it was found that the composition of hydroxyapatite coatings deposited on a
titanium substrate depends on the temperature of detonation products and on the …

Osteogenic and long-term antibacterial properties of Sr/Ag-containing TiO 2 microporous coating in vitro and in vivo

H Wang, TX Zheng, NY Yang, Y Li, H Sun… - Journal of Materials …, 2023 - pubs.rsc.org
Bacterial infection and poor osseointegration are two critical issues that need to be solved
for long-term use of titanium implants. As such, Sr/Ag-containing TiO2 microporous coatings …

The effect of strontium content on physicochemical and osteogenic property of Sr/Ag‐containing TiO2 microporous coatings

YR Wang, NY Yang, H Sun, W Dong… - … Research Part B …, 2023 - Wiley Online Library
Strontium (Sr) is the most common element introduced into TiO2 coatings to strengthen the
osteogenic property of titanium implants. However, the optimal Sr content and its effect on …

[HTML][HTML] Antibacterial and cytocompatible: combining silver nitrate with strontium acetate increases the therapeutic window

MK Parizi, K Doll, MI Rahim, C Mikolai… - International Journal of …, 2022 - mdpi.com
Microbial infection and insufficient tissue formation are considered to be the two main
causes of dental implant failure. Novel studies have focused on designing dual-functional …

The pathogenicity and virulence of the opportunistic pathogen Staphylococcus epidermidis

Ó Burke, MS Zeden, JP O'Gara - Virulence, 2024 - Taylor & Francis
The pervasive presence of Staphylococcus epidermidis and other coagulase-negative
staphylococci on the skin and mucous membranes has long underpinned a casual …

Advances in antimicrobial orthopaedic devices and FDA regulatory challenges

M Kazemzadeh-Narbat, A Memic… - Progress in …, 2024 - iopscience.iop.org
Implant-associated infections, caused by the formation of biofilms especially antibiotic
resistant organisms, are among the leading causes of orthopaedic implant failure. Current …

[HTML][HTML] Enhancement of antibacterial properties and biocompatibility of Ti6Al4V by graphene oxide/strontium nanocomposite electrodepositing

X Wang, W Diwu, J Guo, M Yan, W Ma, M Yang… - Biochemical and …, 2023 - Elsevier
Ti 6 Al 4 V is a widely used orthopedic implant material in clinics. Due to its poor
antibacterial properties, surface modification is required to prevent peri-implantation …