Ischemic stroke involves a series of complex pathological mechanisms, of which
neuroinflammation is currently the most widely recognized. C–C motif chemokine receptor 5 …

Chemokine receptors play crucial roles in fundamental biological processes. Their
malfunction may result in many diseases, including cancer, autoimmune diseases, and HIV …

Ethnopharmacological relevance Infection and inflammation are critical to global human
health status and the goal of current pharmacological interventions intends formulating …

Diabetes is a noncommunicable widespread disease that poses the risk of severe
complications in patients, with certain complications being life-threatening. Hepatitis C is an …

Since the 1950s, great efforts have been made to develop antiviral agents against many
infectious diseases such as human immunodeficiency virus (HIV), hepatitis B virus (HBV) …

Background Asthma is a chronic inflammatory disease that shows a time-of-day response to
variations in symptoms/severity. However, how the lung circadian clock influences time-of …

The ability of tumors to establish a pro-tumorigenic microenvironment is an important point of
investigation in the search for new therapeutics. Tumors form microenvironments in part by …

Behçet's disease (BD), a chronic vascular inflammatory disease, is characterized by the
symptoms of ocular lesions, recurrent genital and oral ulcers, skin symptoms and arthritis in …

Deciphering the molecular alterations leading to disease initiation and progression is
currently crucial to identify the most relevant targets for precision therapy in cancer patients …

One of the greatest challenges in improving prostate cancer (PCa) survival is in designing
new therapies to effectively target bone metastases. PCa regulation of the bone environment …