CCR5D32 in Brazil: Impacts of a European Genetic Variant on a Highly Admixed Population

B Kulmann-Leal, JH Ellwanger… - CCR5: A Receptor at the …, 2022 - books.google.com
Until the year 1500 CE, Brazil was inhabited only by Native Americans belonging to different
linguistic groups, distributed along the coast and hinterland of the country. This scenario …

Novel Small-Molecule Atypical Chemokine Receptor 3 (ACKR3) Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy

A Bayrak, M Szpakowska, V Dicenta-Baunach… - 2024 - chemrxiv.org
Cardiovascular diseases are one of the leading causes of mortality worldwide. Therefore,
novel therapeutic measures are urgently needed, and promising new drug targets must be …

Mutations in rhodopsin, endothelin B receptor, and CC chemokine receptor 5 in large animals: Modeling human diseases

RL Ji, YX Tao - Progress in Molecular Biology and Translational …, 2022 - Elsevier
G protein-coupled receptors (GPCRs) are the largest family of cell membrane receptors
involved in modulating almost all physiological processes by transducing extracellular …

Shaping of the Immune Landscape by Chemokine Receptors that Impacts the Clinical Outcome in Triple-Negative Breast Cancer

D Dulal, AR Boring, D Terrero, AK Tiwari, D Raman - 2022 - Springer
Chronic inflammation triggers a cytokine or chemokine storm in the tissue microenvironment.
The unresolved, persistent inflammatory microenvironment has a tendency to initiate tumors …

Fibroblast-based FN1CFD contributes to parathyroid cancer identification using integrated analysis

R Shen, W Yang, X Liu, J Wang, D Feng, L Zhao… - 2023 - researchsquare.com
Parathyroid cancer (PC) is a highly aggressive cancer with high relapse and metastasis rate.
However, there still lack effective preoperative and intraoperative ways to discriminate …

Estudio de perfil de expresión genética en micosis fungoide como marcador pronóstico

V Gargallo Moneva - 2024 - docta.ucm.es
La micosis fungoide es el linfoma primario cutáneo de células T más frecuente.(1) Se
caracteriza por la infiltración de células T tumorales (en la mayoría de los casos linfocitos T …

Bioinformatics-based identification of key pathways and hub genes of traumatic brain injury in a rat model

X Cao, X Qian, G Liu, Y Wang - Current Medical Science, 2021 - Springer
Traumatic brain injury (TBI) is a common injury caused by external forces that lead to
damaged brain function or pathological changes in the brain tissue. To explore the …

[PDF][PDF] Caractérisation de l'activité biologique des précurseurs et dérivés de la norbelladine

MP Girard - 2023 - depot-e.uqtr.ca
Les virus à ARN sont reconnus comme étant la classe d'agents pathogènes la plus souvent
responsable de l'apparition de nouvelles maladies humaines. Par exemple, le virus de la …

Inflammatory actions of chemokines and extracellular versicles in pathological tissue remodeling

D Kaczor - 2022 - cris.maastrichtuniversity.nl
This thesis gives the reader the general overview on the importance of platelets and smooth
muscle cells in the process of calcification of blood vessels that occurs in various …

[PDF][PDF] Diagnosis of Coronavirus Disease 2019 by Potential Laboratory Factors

P Yazdanpanah, F Vafaei, S Afrouz - Journal of Clinical Care and …, 2022 - jccs.yums.ac.ir
Aims: COVID-19 is associated with infection and high death rate. The unresolved questions
about the fatality rate of COVID-19 is most probably related to cytokine storm syndrome …