Malaria elimination has recently been reinstated as a global health priority but current
therapies seem to be insufficient for the task. Elimination efforts require new drug classes …

In 2019, the world suffered from the emergence of COVID-19 infection, one of the most
difficult pandemics in recent history. Millions of confirmed deaths from this pandemic have …

This digest covers some of the most relevant progress in malaria drug discovery published
between 2010 and 2012. There is an urgent need to develop new antimalarial drugs. Such …

Background Chemodynamic therapy (CDT) relying on intracellular iron ions and H2O2 is a
promising therapeutic strategy due to its tumor selectivity, which is limited by the not enough …

The resistance of malaria parasites to existing drugs carries on growing and progressively
limiting our ability to manage this severe disease and finally lead to a massive global health …

Lung cancer recruits tumor-associated macrophages (TAMs) massively, whose
predominantly pro-tumor M2 phenotype leads to immunosuppression. Dihydroartemisinin …

Colitis-associated colorectal cancer (CAC) develops from chronic intestinal inflammation.
Dihydroartemisinin (DHA) is an antimalarial drug exhibiting anti-inflammatory and anti-tumor …

Photodynamic therapy (PDT) is noninvasive, low toxicity, and photo-selective, but may be
resisted by malignant cells. A previous study found chlorin e6 (Ce6) mediated PDT showed …

Epidermal growth factor receptor (EGFR), also known as ErbB-1/HER-1, plays a key role in
the regulation of the cell proliferation, migration, differentiation, and survival. Since the …

ABSTRACT According to the World Health Organization, malaria remains one of the biggest
public health problems in the world. The development of resistance is a current concern …