[HTML][HTML] Efficacy of colchicine in the treatment of COVID-19 patients: A systematic review and meta-analysis

CJ Toro-Huamanchumo, JK Benites-Meza… - Journal of Clinical …, 2022 - mdpi.com
Objective: We assessed the efficacy of colchicine in COVID-19 patients through a systematic
review. Methods: Six databases were searched until March 2022 for studies assessing …

[HTML][HTML] Therapeutic role of neutralizing antibody for the treatment against SARS-CoV-2 and its emerging variants: a clinical and pre-clinical perspective

M Bhattacharya, S Chatterjee, B Mallik, AR Sharma… - Vaccines, 2022 - mdpi.com
Since early 2020, the entire world has been facing a disastrous outbreak of the SARS-CoV-2
virus, with massive reporting of death and infections per day. Medical practitioners adopted …

[HTML][HTML] COVID-19 and X-linked agammaglobulinemia (XLA)–insights from a monogenic antibody deficiency

MJ Ponsford, BMJ Shillitoe, IR Humphreys… - Current Opinion in …, 2021 - journals.lww.com
In contrast to reports made early in the pandemic, we show XLA patients remain susceptible
to severe disease. Persistent infection was common and is likely to carry a significant …

[HTML][HTML] Aspirin in COVID-19: Pros and cons

R Zareef, M Diab, T Al Saleh, A Makarem… - Frontiers in …, 2022 - frontiersin.org
Since its emergence, the COVID-19 pandemic has been ravaging the medical and
economic sectors even with the significant vaccination advances. In severe presentations …

[HTML][HTML] Repurposing colchicine in treating patients with COVID-19: a systematic review and meta-analysis

CH Lien, MD Lee, SL Weng, CH Lin, LYM Liu, YL Tai… - Life, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19) had caused huge health losses worldwide. Several
drugs had been applied to treat patients with COVID-19, and repurposing colchicine had …

Hyperimmune globulin for severely immunocompromised patients hospitalized with coronavirus disease 2019: a randomized, controlled trial

S Huygens, Q Hofsink, IS Nijhof… - The Journal of …, 2023 - academic.oup.com
Background The aim of this randomized, controlled trial is to determine whether antisevere
acute respiratory syndrome coronavirus 2 hyperimmune globulin (COVIG) protects against …

[HTML][HTML] Pathogenic basis of thromboinflammation and endothelial injury in COVID-19: current findings and therapeutic implications

Y Higashikuni, W Liu, T Obana, M Sata - International Journal of …, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has become a global pandemic with a great impact on social …

Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants

M Korenkov, M Zehner, H Cohen-Dvashi… - Immunity, 2023 - cell.com
Somatic hypermutation (SHM) drives affinity maturation and continues over months in SARS-
CoV-2-neutralizing antibodies (nAbs). However, several potent SARS-CoV-2 antibodies …

The impact of therapeutics on mortality in hospitalised patients with COVID-19: systematic review and meta-analyses informing the European Respiratory Society …

ML Crichton, PC Goeminne, K Tuand… - European …, 2021 - Eur Respiratory Soc
Hospitalised patients with coronavirus disease 2019 (COVID-19) have a high mortality rate.
There are an increasing number of published randomised controlled trials for anti …

Low anti‐SARS‐CoV‐2 S antibody levels predict increased mortality and dissemination of viral components in the blood of critical COVID‐19 patients

M Martin‐Vicente, R Almansa, I Martínez… - Journal of Internal …, 2022 - Wiley Online Library
Abstract Background Anti‐SARS‐CoV‐2 S antibodies prevent viral replication. Critically ill
COVID‐19 patients show viral material in plasma, associated with a dysregulated host …