[HTML][HTML] Role of antibodies, inflammatory markers, and echocardiographic findings in postacute cardiopulmonary symptoms after SARS-CoV-2 infection

MS Durstenfeld, MJ Peluso, JD Kelly, S Win… - JCI insight, 2022 - ncbi.nlm.nih.gov
Shortness of breath, chest pain, and palpitations occur as postacute sequelae of COVID-19,
but whether symptoms are associated with echocardiographic abnormalities, cardiac …

SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19

C Hirsch, YS Park, V Piechotta, KL Chai… - Cochrane Database …, 2022 - cochranelibrary.com
Background Monoclonal antibodies (mAbs) are laboratory‐produced molecules derived
from the B cells of an infected host. They are being investigated as potential prophylaxis to …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

NLRP3 inflammasome and interleukin-1 contributions to COVID-19-associated coagulopathy and immunothrombosis

N Potere, E Garrad, Y Kanthi, M Di Nisio… - Cardiovascular …, 2023 - academic.oup.com
Immunothrombosis—immune-mediated activation of coagulation—is protective against
pathogens, but excessive immunothrombosis can result in pathological thrombosis and …

Colchicine and the combination of rivaroxaban and aspirin in patients hospitalised with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial

JW Eikelboom, SS Jolly, EP Belley-Cote… - The Lancet …, 2022 - thelancet.com
Background COVID-19 disease is accompanied by a dysregulated immune response and
hypercoagulability. The Anti-Coronavirus Therapies (ACT) inpatient trial aimed to evaluate …

Social media and COVID-19—perceptions and public deceptions of ivermectin, colchicine and hydroxychloroquine: lessons for future pandemics

N Schellack, M Strydom, MS Pepper, CL Herd… - Antibiotics, 2022 - mdpi.com
The capacity for social media to influence the utilization of re-purposed medicines to
manage COVID-19, despite limited availability of safety and efficacy data, is a cause for …

Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: a population-based study

RK Topless, A Gaffo, LK Stamp… - The Lancet …, 2022 - thelancet.com
Background There is a paucity of data on outcomes for people with gout and COVID-19. We
aimed to assess whether gout is a risk factor for diagnosis of COVID-19 and COVID-19 …

Effect of colchicine vs usual care alone on intubation and 28-day mortality in patients hospitalized with COVID-19: a randomized clinical trial

R Diaz, A Orlandini, N Castellana, A Caccavo… - JAMA Network …, 2021 - jamanetwork.com
Importance Hospitalized patients with COVID-19 pneumonia have high rates of morbidity
and mortality. Objective To assess the efficacy of colchicine in hospitalized patients with …

Inhalable neutralizing antibodies–promising approach to combating respiratory viral infections

MYT Chow, HW Pan, HC Seow, JKW Lam - Trends in pharmacological …, 2023 - cell.com
Monoclonal antibodies represent an exciting class of therapeutics against respiratory viral
infections. Notwithstanding their specificity and affinity, the conventional parenteral …

Synthesis of Seleno-Dibenzocycloheptenones/Spiro [5.5] Trienones by Radical Cyclization of Biaryl Ynones

HA Goulart, RH Bartz, TJ Peglow… - The Journal of …, 2022 - ACS Publications
We report herein an alternative method for the synthesis of seleno-dibenzocycloheptenones
and seleno-spiro [5.5] trienones through the radical cyclization of biaryl ynones in the …