Noncoding RNAs: master regulator of fibroblast to myofibroblast transition in fibrosis
H Zhang, Y Zhou, D Wen, J Wang - International Journal of Molecular …, 2023 - mdpi.com
Myofibroblasts escape apoptosis and proliferate abnormally under pathological conditions,
especially fibrosis; they synthesize and secrete a large amount of extracellular matrix (ECM) …
especially fibrosis; they synthesize and secrete a large amount of extracellular matrix (ECM) …
Circular RNAs in acute kidney injury: roles in pathophysiology and implications for clinical management
Acute kidney injury (AKI) is a common clinical condition, results in patient morbidity and
mortality, and incurs considerable health care costs. Sepsis, ischaemia-reperfusion injury …
mortality, and incurs considerable health care costs. Sepsis, ischaemia-reperfusion injury …
Proximal tubular RAGE mediated the renal fibrosis in UUO model mice via upregulation of autophagy
B Liu, T Sun, H Li, S Qiu, Y Li, D Zhang - Cell Death & Disease, 2022 - nature.com
Previous studies reported that RAGE participated in the process of kidney fibrosis, but the
function and regulation pathway of RAGE in proximal tubular cells in this process remains …
function and regulation pathway of RAGE in proximal tubular cells in this process remains …
[HTML][HTML] Function of hsa_circ_0006646 as a competing endogenous RNA to promote progression in gastric cancer by regulating the miR-665–HMGB1 axis
J Qin, S Zhen, J Wang, W Lv, Y Zhao… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background Mounting evidences indicate that circular RNAs (circRNAs) are a novel class of
non-coding RNAs and play vital roles in the tumorigenesis and aggressiveness including …
non-coding RNAs and play vital roles in the tumorigenesis and aggressiveness including …
CircInpp5b Ameliorates Renal Interstitial Fibrosis by Promoting the Lysosomal Degradation of DDX1
X Fang, C Tang, D Zeng, Y Shan, Q Liu, X Yin, Y Li - Biomolecules, 2024 - mdpi.com
Renal interstitial fibrosis (RIF) is a classic pathophysiological process of chronic kidney
disease (CKD). However, the mechanisms underlying RIF remain unclear. The present …
disease (CKD). However, the mechanisms underlying RIF remain unclear. The present …
Circular RNA circVmn2r1 acts as a miR-223-3p sponge to promote kidney aging by regulating NLRP3 expression in mice
F Gao, L Wei, J Li, L Zeng, M Wang… - The Journals of …, 2024 - academic.oup.com
Kidney aging accelerates the progression of various acute and chronic kidney diseases and
can also induce pathological changes in other organs throughout the body. Circular RNAs …
can also induce pathological changes in other organs throughout the body. Circular RNAs …
Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression
J Zhou, P Li, X Zhao, Y Zhao, J Luo, Y Deng… - Respiratory …, 2023 - Springer
Background Lung cancer represents a significant public health issue in China, given its high
incidence and mortality rates. Circular RNAs (circRNAs) have been recently proposed to …
incidence and mortality rates. Circular RNAs (circRNAs) have been recently proposed to …
[PDF][PDF] 环状RNA KIF4A 在结直肠癌中表达与功能及其作用机制
吴明浩， 夏绿洲， 张渝 - 中国普通外科杂志, 2023 - zpwz.net
摘要背景与目的: 环状RNA KIF4A (circKIF4A) 被发现在多种肿瘤的恶性进展中起到重要作用,
然而, circKIF4A 在结直肠癌中的生物学作用尚未见报道. 因此, 本研究探讨circKIF4A …
然而, circKIF4A 在结直肠癌中的生物学作用尚未见报道. 因此, 本研究探讨circKIF4A …
Genome-wide analysis of circular RNA-mediated ceRNA regulation in porcine skeletal muscle development
J Yun, X Huang, C Liu, M Shi, W Li, J Niu, C Cai… - BMC genomics, 2023 - Springer
Background As a diverse and abundant class of endogenous RNAs, circular RNAs
(circRNAs) participate in various biological processes including cell proliferation and …
(circRNAs) participate in various biological processes including cell proliferation and …
RfxCas13d-mediated inhibition of Circ1647 alleviates renal fibrosis via PI3K/AKT signaling pathway
Y Ni, H Zhang, Q Xian, W Qin, H Su, L Wang, J Li - Renal Failure, 2024 - Taylor & Francis
Abstract Background Circular RNAs (CircRNAs) have been shown to be involved in the
development of chronic kidney disease (CKD). This study aimed to investigate the role of …
development of chronic kidney disease (CKD). This study aimed to investigate the role of …