Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

JC Wang, R Grucza, C Cruchaga, AL Hinrichs… - Molecular …, 2009 - nature.com
Alcohol dependence frequently co-occurs with cigarette smoking, another common addictive
behavior. Evidence from genetic studies demonstrates that alcohol dependence and …

Genome-wide copy number variation analysis in attention-deficit/hyperactivity disorder: association with neuropeptide Y gene dosage in an extended pedigree

KP Lesch, S Selch, TJ Renner, C Jacob… - Molecular …, 2011 - nature.com
Attention-deficit/hyperactivity disorder (ADHD) is a common, highly heritable
neurodevelopmental syndrome characterized by hyperactivity, inattention and increased …

Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis

A Cobat, CJ Gallant, L Simkin, GF Black… - Journal of Experimental …, 2009 - rupress.org
Approximately 20% of persons living in areas hyperendemic for tuberculosis (TB) display
persistent lack of tuberculin skin test (TST) reactivity and appear to be naturally resistant to …

[HTML][HTML] The BTNL2 gene and sarcoidosis susceptibility in African Americans and Whites

BA Rybicki, JL Walewski, MJ Maliarik, H Kian… - The American Journal of …, 2005 - cell.com
The BTNL2 gene is a member of the B7 receptor family that probably functions as a T-cell
costimulatory molecule. It resides in the class II major histocompatibility complex (MHC) …

Pharmacogenetic differences in response to albuterol between Puerto Ricans and Mexicans with asthma

S Choudhry, N Ung, PC Avila, E Ziv… - American journal of …, 2005 - atsjournals.org
Background: In the United States, Puerto Ricans and Mexicans have the highest and lowest
asthma prevalence, morbidity, and mortality, respectively. Ethnic-specific differences in the …

Case/pseudocontrol analysis in genetic association studies: A unified framework for detection of genotype and haplotype associations, gene‐gene and gene …

HJ Cordell, BJ Barratt… - Genetic Epidemiology: The …, 2004 - Wiley Online Library
Estimation and testing of genetic effects (genotype relative risks) are often performed
conditionally on parental genotypes, using data from case‐parent trios. This strategy avoids …

[HTML][HTML] Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q

MB McQueen, B Devlin, SV Faraone… - The American Journal of …, 2005 - cell.com
Several independent studies and meta-analyses aimed at identifying genomic regions
linked to bipolar disorder (BP) have failed to find clear and consistent evidence of linkage …

[HTML][HTML] Musical aptitude is associated with AVPR1A-haplotypes

LT Ukkola, P Onkamo, P Raijas, K Karma, I Järvelä - PLoS One, 2009 - journals.plos.org
Artistic creativity forms the basis of music culture and music industry. Composing,
improvising and arranging music are complex creative functions of the human brain, which …

[图书][B] The fundamentals of modern statistical genetics

NM Laird, C Lange - 2011 - Springer
Provides cutting edge coverage of current gene mapping approaches grounded in a
traditional statistical genetics framework, with emphasis on association studies Provides …

[HTML][HTML] Comparison of methods to account for relatedness in genome-wide association studies with family-based data

J Eu-Ahsunthornwattana, EN Miller, M Fakiola… - PLoS …, 2014 - journals.plos.org
Approaches based on linear mixed models (LMMs) have recently gained popularity for
modelling population substructure and relatedness in genome-wide association studies. In …