Three waves changes, new variant strains, and vaccination effect against COVID-19 pandemic

RM El-Shabasy, MA Nayel, MM Taher… - International Journal of …, 2022 - Elsevier
It has been more than one year since the first case of the coronaviruses was infected by
COVID-19 in China. The world witnessed three waves of the corona virus till now, and more …

[PDF][PDF] Adaptive immunity to SARS-CoV-2 and COVID-19

A Sette, S Crotty - Cell, 2021 - cell.com
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …

Immune correlates of protection by mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates

KS Corbett, MC Nason, B Flach, M Gagne, S O'Connell… - Science, 2021 - science.org
INTRODUCTION Mass vaccination against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) offers the most efficient public health intervention to control the COVID-19 …

Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models

HY Huang, HY Liao, X Chen, SW Wang… - Science Translational …, 2022 - science.org
A major challenge to end the pandemic caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is to develop a broadly protective vaccine that elicits long-term …

Scientific rationale for developing potent RBD-based vaccines targeting COVID-19

H Kleanthous, JM Silverman, KW Makar, IK Yoon… - npj Vaccines, 2021 - nature.com
Vaccination of the global population against COVID-19 is a great scientific, logistical, and
moral challenge. Despite the rapid development and authorization of several full-length …

Protection against SARS-CoV-2 Beta variant in mRNA-1273 vaccine–boosted nonhuman primates

KS Corbett, M Gagne, DA Wagner, S O'Connell… - Science, 2021 - science.org
Neutralizing antibody responses gradually wane against several variants of concern (VOCs)
after vaccination with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

[PDF][PDF] Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

PJM Brouwer, M Brinkkemper, P Maisonnasse… - Cell, 2021 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is
continuing to disrupt personal lives, global healthcare systems, and economies. Hence …

[HTML][HTML] Antibody responses to SARS-CoV-2 mRNA vaccines are detectable in saliva

TJ Ketas, D Chaturbhuj, VMC Portillo… - Pathogens and …, 2021 - ncbi.nlm.nih.gov
Abstract The approved Pfizer and Moderna mRNA vaccines are well known to induce serum
antibody responses to the SARS-CoV-2 Spike (S)-protein. However, their abilities to elicit …

A summary of the SARS-CoV-2 vaccines and technologies available or under development

ZA Abdulla, SM Al-Bashir, NS Al-Salih, AA Aldamen… - Pathogens, 2021 - mdpi.com
Since the beginning of 2020, the world has been in a race to develop vaccines that can
control the COVID-19 pandemic. More than 250 projects have been initiated for this …

Humoral immune response after different SARS-CoV-2 vaccination regimens

R Rose, F Neumann, O Grobe, T Lorentz… - BMC medicine, 2022 - Springer
Background The humoral immune response after primary immunisation with a SARS-CoV-2
vector vaccine (AstraZeneca AZD1222, ChAdOx1 nCoV-19, Vaxzevria) followed by an …