The causative agent of the COVID-19 pandemic is undergoing several changes, and the
evolutionary cascade of SARS-CoV-2 has led to the emergence of a range of variants of …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has caused
an ongoing global health crisis. Here, we present as a vaccine candidate synthetic SARS …

The coronavirus disease of 2019 (COVID-19), caused by infection with the severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) has undoubtedly been the most …

Abstract Vaccine-elicited SARS-CoV-2 antibody responses are an established correlate of
protection against viral infection in humans and nonhuman primates. However, it is less …

Less than 18 months after the identification of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and its genome, 13 authorized or approved COVID-19 …

We assessed the humoral immune responses to a COVID-19 vaccine in a well-controlled
rhesus macaque model compared to humans immunized with two mRNA vaccines over …

Background Vaccine efficacy against the B. 1.351 variant following mRNA-1273 vaccination
in humans has not been determined. Nonhuman primates (NHP) are a useful model for …

The SARS-CoV-2 pandemic has again shown that structural biology plays an important role
in understanding biological mechanisms and exploiting structural data for therapeutic …

The enzyme-linked immunosorbent spot (ELISpot) assay is a powerful in vitro immunoassay
that enables cost-effective quantification of antigen-specific T-cell reactivity. It is used widely …

Real-world evidence of the vaccine effectiveness (VE) of different COVID-19 vaccines is
needed in order to better shape vaccine recommendations and policies and increase …