Smilax china L.: A review of its botany, ethnopharmacology, phytochemistry, pharmacological activities, actual and potential applications

M Wang, QX Bai, XX Zheng, WJ Hu, S Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Smilax china L., an extensively used traditional Chinese
medicine, is known as Baqia in China. It has been used to treat various inflammatory …

Advances in health-promoting effects of natural polysaccharides: Regulation on Nrf2 antioxidant pathway

JH Luo, J Li, ZC Shen, XF Lin, AQ Chen… - Frontiers in …, 2023 - frontiersin.org
Natural polysaccharides (NPs) possess numerous health-promoting effects, such as liver
protection, kidney protection, lung protection, neuroprotection, cardioprotection …

[HTML][HTML] Leonurine alleviates acetaminophen-induced acute liver injury by regulating the PI3K/AKT signaling pathway in mice

Y Yu, S Zhou, Y Wang, S Di, Y Wang, X Huang… - International …, 2023 - Elsevier
Leonurine (Leo) is a natural alkaloid isolated from the herb Leonurus japonicus
Houtt.(Leonuri) that has been shown to inhibit oxidative stress and inflammation. However …

Smilax China L. polysaccharide prevents HFD induced-NAFLD by regulating hepatic fat metabolism and gut microbiota

W Zhang, L Yu, Q Yang, J Zhang, W Wang, X Hu, J Li… - Phytomedicine, 2024 - Elsevier
Background The increasing incidence of nonalcoholic fatty liver disease (NAFLD) has urged
the development of new therapeutics. NAFLD is intimately linked to gut microbiota due to the …

[HTML][HTML] Human umbilical cord-derived mesenchymal stem cells ameliorate liver fibrosis by improving mitochondrial function via Slc25a47-Sirt3 signaling pathway

P Chen, M Yuan, L Yao, Z Xiong, P Liu, Z Wang… - Biomedicine & …, 2024 - Elsevier
Chronic Liver fibrosis may progress to liver cirrhosis and hepatocellular carcinoma (HCC),
hence cause a substantial global burden. However, effective therapies for blocking fibrosis …

Gualou-Xiebai herb pair ameliorate atherosclerosis in HFD-induced ApoE−/− mice and inhibit the ox-LDL-induced injury of HUVECs by regulating the Nrf2-mediated …

L Zhu, Y Bao, Z Liu, J Liu, Z Li, X Sun, A Zhou… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Atherosclerosis (AS) is a chronic vascular ailment
characterized by inflammatory and lipid deposition in the arterial wall caused by endothelial …

Insights into the molecular mechanisms, structure-activity relationships and application prospects of polysaccharides by regulating Nrf2-mediated antioxidant …

N Chen, M Hu, T Jiang, P Xiao, J Duan - Carbohydrate Polymers, 2024 - Elsevier
The occurrence and development of many diseases are closely related to oxidative stress. In
this context, accumulating evidence suggests that Nrf2, as the master switch of cellular …

Natural Products for Acetaminophen-Induced Acute Liver Injury: A Review

X Li, R Lao, J Lei, Y Chen, Q Zhou, T Wang, Y Tong - Molecules, 2023 - mdpi.com
The liver plays a vital role in metabolism, synthesis, and detoxification, but it is susceptible to
damage from various factors such as viral infections, drug reactions, excessive alcohol …

[HTML][HTML] Enzymatic-extractable polysaccharides from Cordyceps militaris alleviate carbon tetrachloride-induced liver injury via Nrf2/ROS/NF-κB signaling pathway

H Zhao, B Deng, D Li, L Jia, F Yang - Journal of Functional Foods, 2022 - Elsevier
Cordyceps militaris polysaccharides have aroused attention due to extensive physiological
activities. One novel enzymatic-extractable polysaccharide, EPCMa, was obtained by …

Intestinal lymphatic transport of Smilax china L. pectic polysaccharide via Peyer's patches and its uptake and transport mechanisms in mononuclear phagocytes

J Liu, X Zhang, Y Liu, Z Wu, Z Cui, X Pan, Y Zheng… - Carbohydrate …, 2024 - Elsevier
Recently, the intestinal lymphatic transport based on Peyer's patches (PPs) is emerging as a
promising absorption pathway for natural polysaccharides. Herein, the aim of this study is to …