The effect of vitamin D plus protein supplementation on sarcopenia: A systematic review and meta-analysis of randomized controlled trials

NK Gkekas, P Anagnostis, V Paraschou, D Stamiris… - Maturitas, 2021 - Elsevier
Purpose The exact effect of vitamin D supplementation, either as monotherapy or in
combination with protein, on musculoskeletal health in patients with sarcopenia is currently …

Current therapeutic targets in cancer cachexia: a pathophysiologic approach

KC Kadakia, JM Hamilton-Reeves… - American Society of …, 2023 - ascopubs.org
Significant progress in our understanding of cancer cachexia has occurred in recent years.
Despite these advances, no pharmacologic agent has achieved US Food and Drug …

Protein intake and muscle mass maintenance in patients with cancer types with high prevalence of sarcopenia: a systematic review

C Capitão, D Coutinho, PM Neves, ML Capelas… - Supportive Care in …, 2022 - Springer
Rationale Cancer is associated with muscle wasting. However, optimal protein intake has
not been determined, limiting the efficacy of nutritional interventions. This systematic review …

[HTML][HTML] Chemotherapy-induced molecular changes in skeletal muscle

MB Pedrosa, S Barbosa, R Vitorino, R Ferreira… - Biomedicines, 2023 - mdpi.com
Paraneoplastic conditions such as cancer cachexia are often exacerbated by chemotherapy,
which affects the patient's quality of life as well as the response to therapy. The aim of this …

[HTML][HTML] Nicotinamide mononucleotide administration prevents doxorubicin-induced cardiotoxicity and loss in physical activity in mice

M Margier, C Kuehnemann, N Hulo, J Morales… - Cells, 2022 - mdpi.com
Doxorubicin (Doxo) is a widely used antineoplastic drug with limited clinical application due
to its deleterious dose-related side effects. We investigated whether nicotinamide …

[HTML][HTML] Current insights in nutrition assessment and intervention for malnutrition or muscle loss in people with lung cancer: a narrative review

N Kiss, A Curtis - Advances in Nutrition, 2022 - Elsevier
Up to 70% of people with lung cancer may be affected by cancer-related malnutrition or
muscle loss, depending on treatment modality and disease stage. This narrative review …

Assessing dynamic change in muscle during treatment of patients with cancer: precision testing standards

L Arribas, A Sabaté-Llobera, MC Domingo, M Taberna… - Clinical Nutrition, 2022 - Elsevier
Background Computed tomography images acquired during routine cancer care provide an
opportunity to determine body composition with accuracy and precision. Quantification of …

Prognostic impact of the loss of skeletal muscle mass during neoadjuvant chemotherapy on older patients with esophageal cancer

T Harada, T Tsuji, J Ueno, Y Koishihara… - Annals of Surgical …, 2022 - Springer
Background In older adults, skeletal muscle mass is an important factor for health and
prognosis. The loss of SMM during neoadjuvant therapy affects the prognosis of patients …

CT-defined low-skeletal muscle mass as a prognostic marker for survival in prostate cancer: a systematic review and meta-analysis

HJ Meyer, A Wienke, A Surov - Urologic Oncology: Seminars and Original …, 2022 - Elsevier
Background Low-skeletal muscle mass (LSMM) is defined as progressive skeletal muscle
loss, which can be assessed by imaging modalities. It was shown that this parameter is …

Adverse effects of systemic cancer therapy on skeletal muscle: myotoxicity comes out of the closet

P Klassen, DL Schiessel… - Current Opinion in Clinical …, 2023 - journals.lww.com
The adverse side effect of cancer therapy on skeletal muscle has been largely ignored in the
development of cancer therapeutics. Given the extent to which loss of muscle mass and …