The evolution of tumour composition during fractionated radiotherapy: implications for outcome

TD Lewin, PK Maini, EG Moros, H Enderling… - Bulletin of Mathematical …, 2018 - Springer
Current protocols for delivering radiotherapy are based primarily on tumour stage and nodal
and metastases status, even though it is well known that tumours and their …

On the immunological consequences of conventionally fractionated radiotherapy

JCL Alfonso, LA Papaxenopoulou, P Mascheroni… - Iscience, 2020 - cell.com
Emerging evidence demonstrates that radiotherapy induces immunogenic death on tumor
cells that emit immunostimulating signals resulting in tumor-specific immune responses …

Predicting radiotherapy patient outcomes with real-time clinical data using mathematical modelling

AP Browning, TD Lewin, RE Baker, PK Maini… - Bulletin of mathematical …, 2024 - Springer
Longitudinal tumour volume data from head-and-neck cancer patients show that tumours of
comparable pre-treatment size and stage may respond very differently to the same …

The physics of physik

SW Smye - Journal of the Royal College of Physicians of …, 2018 - journals.sagepub.com
When you can measure what you are speaking about, and express it in numbers, you know
something about it. When you cannot express it in numbers, your knowledge is of a meagre …

Modelling the impact of heterogeneity in tumour composition on the response to fractionated radiotherapy

T Lewin - 2018 - ora.ox.ac.uk
Current protocols for delivering radiotherapy are based primarily on tumour stage and nodal
and metastases (TNM) status, even though it is well known that tumours and their …

Interstitial Fluid Flow and Transport in Glioblastoma and Surrounding Parenchyma in Patients

K Chatterjee, N Atay, D Abler, S Bhargava, P Sahoo… - 2020 - preprints.org
Background: Glioblastoma is the deadliest, yet most common, brain tumor in adults, with
poor survival and response to aggressive therapy. Therapeutic failure results from a number …

Simulation of Radiotherapy Effects on Destroying Cancer Cells and Cancer Stem Cells

G Aghebati, N Naghavi, B Gheflati… - 2020 27th National …, 2020 - ieeexplore.ieee.org
Radiotherapy is a common method for cancer treatment. One of the factors that determine
the tumor's malignancy is the presence of cancer stem cells in tumors. These cells not only …

On the Immunological Consequences of Conventionally Fractionated Radiotherapy: In silico Insights

JC Lopez Alfonso, LA Papaxenopoulou… - Available at SSRN …, 2019 - papers.ssrn.com
Emerging evidence demonstrates that radiotherapy induces immunogenic cell death on
tumor cells that emits immunostimulating signals, resulting in tumor-specific local and …