Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 years after the discovery
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38-amino acid C-terminally
α-amidated peptide that was first isolated 20 years ago from an ovine hypothalamic extract …
α-amidated peptide that was first isolated 20 years ago from an ovine hypothalamic extract …
Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase‐activating polypeptide: IUPHAR review 1
Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase‐activating polypeptide
(PACAP) are members of a superfamily of structurally related peptide hormones that …
(PACAP) are members of a superfamily of structurally related peptide hormones that …
Neuronal control of skin function: the skin as a neuroimmunoendocrine organ
D Roosterman, T Goerge, SW Schneider… - Physiological …, 2006 - journals.physiology.org
This review focuses on the role of the peripheral nervous system in cutaneous biology and
disease. During the last few years, a modern concept of an interactive network between …
disease. During the last few years, a modern concept of an interactive network between …
Pituitary adenylate cyclase-activating polypeptide and its receptors: from structure to functions
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38-amino acid peptide that
was first isolated from ovine hypothalamic extracts on the basis of its ability to stimulate …
was first isolated from ovine hypothalamic extracts on the basis of its ability to stimulate …
VPAC and PAC receptors: from ligands to function
L Dickson, K Finlayson - Pharmacology & therapeutics, 2009 - Elsevier
Vasoactive intestinal peptide (VIP) and the pituitary adenylate cyclase activating
polypeptides (PACAPs) share 68% identity at the amino acid level and belong to the …
polypeptides (PACAPs) share 68% identity at the amino acid level and belong to the …
The significance of vasoactive intestinal peptide in immunomodulation
First identified by Said and Mutt some 30 years ago, the vasoactive intestinal peptide (VIP)
was originally isolated as a vasodilator peptide. Subsequently, its biochemistry was …
was originally isolated as a vasodilator peptide. Subsequently, its biochemistry was …
International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide
Vasoactive intestinal peptide (VIPb) and pituitary adenylate cyclase-activating polypeptide
(PACAP) are members of a superfamily of structurally related peptide hormones that …
(PACAP) are members of a superfamily of structurally related peptide hormones that …
Molecular basis of receptor/G-protein-coupling selectivity
J Wess - Pharmacology & therapeutics, 1998 - Elsevier
Molecular cloning studies have shown that G-protein-coupled receptors form one of the
largest protein families found in nature, and it is estimated that approximately 1000 different …
largest protein families found in nature, and it is estimated that approximately 1000 different …
Functional and structural complexity of signal transduction via G-protein-coupled receptors
T Gudermann, T Schöneberg… - Annual review of …, 1997 - annualreviews.org
▪ Abstract A prerequisite for the maintenance of homeostasis in a living organism is fine-
tuned communication between different cells. The majority of extracellular signaling …
tuned communication between different cells. The majority of extracellular signaling …
Immunomodulatory role of neuropeptides in the cornea
The transparency of the cornea along with its dense sensory innervation and resident
leukocyte populations make it an ideal tissue to study interactions between the nervous and …
leukocyte populations make it an ideal tissue to study interactions between the nervous and …