Many enveloped viruses encode late assembly domains, or L domains, that facilitate virion
egress. PTAP-type L domains act by recruiting the ESCRT-I (endosomal sorting complex …

Arenaviruses form a noncytolytic infection in their rodent hosts, yet can elicit severe
hemorrhagic disease in humans. How arenaviruses regulate gene expression remains …

ABSTRACT The New World arenavirus Junin virus (JUNV) is the causative agent of
Argentine hemorrhagic fever (AHF), which is associated with high morbidity and significant …

Arenaviruses are a family of enveloped negative-stranded RNA viruses that can cause
severe human disease ranging from encephalitis symptoms to fulminant hemorrhagic fever …

Marburg virus (MARV) VP40 is a matrix protein that can be released from mammalian cells
in the form of virus-like particles (VLPs) and contains the PPPY sequence, which is an L …

Generation of infectious arenavirus-like particles requires the virus RING finger Z protein
and surface glycoprotein precursor (GPC) and the correct processing of GPC into GP1, GP2 …

Members of Arenaviridae, Bunyaviridae, Filoviridae, and Flaviviridae that cause acute viral
hemorrhagic fever (VHF) have in common the presence of a single-stranded RNA genome …

Viral matrix proteins of several enveloped RNA viruses play important roles in virus
assembly and budding and are by themselves able to bud from the cell surface in the form of …

Highlights•A comprehensive review of the history of Machupo virus.•A review of the clinical
disease Bolivian hemorrhagic fever.•A comprehensive review of animal models for the study …

Crimean-Congo hemorrhagic fever virus (CCHFV; genus Nairovirus) is an extremely
pathogenic member of the Bunyaviridae family. Since handling of the virus requires a …