Stromal mesenchymal stem cells (MSCs) have the capability to self-renew and can
differentiate into multiple cell types of the mesoderm germ layer, but their properties are …

The genetics of human longevity has long been studied, and in this regard, centenarians
represent a very informative model. Centenarians are characterized by 2 main features: 1) …

Natural populations harbor considerable genetic variation for lifespan. While evolutionary
theory provides general explanations for the existence of this variation, our knowledge of the …

The practical pharmacogenetics of Alzheimer's disease (AD) is circumscribed to
acetylcholinesterase inhibitors (AChEIs) and memantine. However, pharmacogenetic …

Many physiological processes in the human body follow a 24-h circadian rhythm controlled
by the circadian clock system. Light, sensed by retina, is the predominant “zeitgeber” able to …

Lycium barbarum berry (Ningxia Gouqi, Fructus lycii, goji berry, or wolfberry), as a traditional
Chinese herb, was recorded beneficial for longevity in traditional Chinese medical …

Sex differences in human survival have been extensively investigated in many studies that
have in part uncovered the biological determinants that promote a longer life in females with …

Some studies have shown that polymorphisms in the insulin growth factor-1 (IGF-1)
signaling pathway genes could influence human longevity. However, the results of different …

With 38 million residents, Poland has the eighth-largest population in Europe. A successful
transition from communism to democracy, which began in 1989, has brought several …

A growing aging population is associated with increasing incidences of aging-related
diseases and socioeconomic burdens. Hence, research into healthy longevity and aging is …