We focus on drug repurposing in the Ras signaling pathway, considering structural
similarities of protein–protein interfaces. The interfaces formed by physically interacting …

The cellular signaling pathway components that control the different stages of cell
maturation such as RTK, PI3K, B‐Raf, and CDK represent crucial antitumor drug targets. The …

Biological systems consist of multiple components of different physical and chemical
properties that require complex and dynamic regulatory loops to function efficiently. The …

Hepatocellular carcinoma (HCC) is a significant contributor to morbidity and mortality
worldwide. The interaction between receptors and ligands is the primary mode of …

Cell Signaling pathways form an integral part of our existence that allows the cells to
comprehend a stimulus and respond back. Such reactions to external cues from the …

Osteoarthritis (OA) is the most common form of arthritis, characterized by osteophyte
formation, cartilage degradation, and structural and cellular alterations of the synovial …

Genomics methods have uncovered patterns in a range of biological systems, but obscure
important aspects of cell behavior: the shape, relative locations of, movement of, and …

Objective: This study was carried out to find out the immunolocalization of Interleukin 6 (IL-6)
and Interleukin 10 (IL-10) in the testicular tissue of testicular dysfunction rat treated with …

This paper reports various types of cancer, their incidence, and prevalence all over the
globe. Along with the discovery of novel natural drugs for cancer treatment, these present a …

Heart failure (HF) has emerged as the most pressing health concerns globally, and extant
clinical therapies are accompanied by side effects and patients have a high burden of …