Pathogenic variants in human DNA damage repair genes mostly arose after the latest human out-of-Africa migration

J He, SH Kou, J Li, X Ding, SM Wang - Frontiers in Genetics, 2024 - frontiersin.org
Introduction The DNA damage repair (DDR) system in human genome is pivotal in
maintaining genomic integrity. Pathogenic variation (PV) in DDR genes impairs their …

Paleolithic Gene Duplications Primed Adaptive Evolution of Human Amylase Locus Upon Agriculture

F Yılmaz, C Karageorgiou, K Kim, P Pajic, K Scheer… - bioRxiv, 2023 - biorxiv.org
Starch digestion is a cornerstone of human nutrition. The amylase genes code for the starch-
digesting amylase enzyme. Previous studies suggested that the salivary amylase (AMY1) …

[PDF][PDF] 20,000 YEARS OF SHARED HISTORY ON THE PERSIAN PLATEAU A novel genetic study sheds light on the location where the ancestors of all present day …

M Petraglia - unipd.it
All present day non African human populations are the result of subdivisions that took place
after their ancestors left Africa at least 60.000 years ago. How long did it take for these …