[HTML][HTML] Advances and opportunities in malaria population genomics

DE Neafsey, AR Taylor, BL MacInnis - Nature Reviews Genetics, 2021 - nature.com
Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

[HTML][HTML] Out of Africa: origins and evolution of the human malaria parasites Plasmodium falciparum and Plasmodium vivax

DE Loy, W Liu, Y Li, GH Learn, LJ Plenderleith… - International journal for …, 2017 - Elsevier
Plasmodium falciparum and Plasmodium vivax account for more than 95% of all human
malaria infections, and thus pose a serious public health challenge. To control and …

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

F Ariey, B Witkowski, C Amaratunga, J Beghain… - Nature, 2014 - nature.com
Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens
malaria control and elimination activities worldwide. To monitor the spread of artemisinin …

[HTML][HTML] An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples

A Ahouidi, M Ali, J Almagro-Garcia… - Wellcome Open …, 2021 - ncbi.nlm.nih.gov
A major obstacle to malaria elimination is the great capacity of the parasite and vector
populations to evolve in response to malaria control interventions. The widespread use of …

GDV1 induces sexual commitment of malaria parasites by antagonizing HP1-dependent gene silencing

M Filarsky, SA Fraschka, I Niederwieser… - Science, 2018 - science.org
Malaria is caused by Plasmodium parasites that proliferate in the bloodstream. During each
replication cycle, some parasites differentiate into gametocytes, the only forms able to infect …

Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans

D Lee, S Zdraljevic, L Stevens, Y Wang… - Nature ecology & …, 2021 - nature.com
Across diverse taxa, selfing species have evolved independently from outcrossing species
thousands of times. The transition from outcrossing to selfing decreases the effective …

Detecting balancing selection in genomes: limits and prospects

A Fijarczyk, W Babik - Molecular ecology, 2015 - Wiley Online Library
In spite of the long‐term interest in the process of balancing selection, its frequency in
genomes and evolutionary significance remain unclear due to challenges related to its …

[图书][B] Population genetics and microevolutionary theory

AR Templeton - 2021 - books.google.com
Population Genetics and Microevolutionary Theory Explore the fundamentals of the
biological implications of population genetic theory In the newly revised Second Edition of …

Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution

X Su, KD Lane, L Xia, JM Sá… - Clinical microbiology …, 2019 - Am Soc Microbiol
Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …

[HTML][HTML] Plasmodium falciparum Erythrocyte Invasion: Combining Function with Immune Evasion

GJ Wright, JC Rayner - PLoS pathogens, 2014 - journals.plos.org
All the symptoms and pathology of malaria are caused by the intraerythrocytic stages of the
Plasmodium parasite life cycle. Because Plasmodium parasites cannot replicate outside a …