Beta-irradiation used for systemic radioimmunotherapy (RIT) is a promising treatment
approach for high-risk leukaemia and lymphoma. In bone marrow-selective …

Taurine chloramine (TN-Cl) is one of the most abundant compounds generated by activated
neutrophils. In contrast to HOCl, which causes necrosis, TN-Cl is a potent inducer of …

Mechanisms related to the neuropathogenesis of enterovirus 71 infection remain unclear.
This investigation conducts a comprehensive study of the apoptotic pathways in neural and …

ADP‐ribosylation is a post‐translational modification that regulates various physiological
processes, including DNA damage repair, gene transcription and signal transduction …

Nephrotoxicity has become prominent due to the increase in the clinical use of nilotinib, a
second‐generation BCR‐ABL1 inhibitor in the first‐line treatment of Philadelphia …

Testicular cancer is the most frequent solid malignant tumour type in men 20–40 years of
age. At the time of diagnosis up to 50% of the patients suffer from metastatic disease. In …

Background Caspase-8 is a key upstream mediator in death receptor-mediated apoptosis
and also participates in mitochondria-mediated apoptosis via cleavage of proapoptotic Bid …

Summary The World Health Organization Classification of Lymphoid Neoplasms identifies
Burkitt's lymphoma/leukaemia (BL) as a single entity, characterized by unique clinical and …

The tomato (Lycopersicon esculentum) fruit is the best available model to study the stress
response of fleshy fruit. Programmed cell death (PCD) plays an important role in stress …

Several cytostatic agents are known to induce apoptosis in T-leukemic cells. Although a
variety of studies show the central role of apoptosis in cytostatic drug-induced cell death …