The inflamed brain in schizophrenia: the convergence of genetic and environmental risk factors that lead to uncontrolled neuroinflammation
Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …
between genetic and environmental risk factors. The immune system is now known to play …
[HTML][HTML] The HPA axis dysregulation in severe mental illness: Can we shift the blame to gut microbiota?
Accumulating evidence indicates that patients with severe mental disorders, including major
depression, bipolar disorder and schizophrenia present with various alterations of the gut …
depression, bipolar disorder and schizophrenia present with various alterations of the gut …
Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma
K Gapp, G van Steenwyk, PL Germain… - Molecular …, 2020 - nature.com
Psychiatric diseases have a strong heritable component known to not be restricted to DNA
sequence-based genetic inheritance alone but to also involve epigenetic factors in germ …
sequence-based genetic inheritance alone but to also involve epigenetic factors in germ …
[HTML][HTML] Epigenetics of childhood trauma: Long term sequelae and potential for treatment
KM Thumfart, A Jawaid, K Bright, M Flachsmann… - Neuroscience & …, 2022 - Elsevier
Childhood trauma (CT) can have persistent effects on the brain and is one of the major risk
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …
factors for neuropsychiatric diseases in adulthood. Recent advances in the field of …
Interactions between variation in candidate genes and environmental factors in the etiology of schizophrenia and bipolar disorder: a systematic review
Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …
A systematic review on mediators between adversity and psychosis: potential targets for treatment
Various psychological and biological pathways have been proposed as mediators between
childhood adversity (CA) and psychosis. A systematic review of the evidence in this domain …
childhood adversity (CA) and psychosis. A systematic review of the evidence in this domain …
Childhood trauma and psychosis: an updated review
KJ Stanton, B Denietolis… - Child and Adolescent …, 2020 - childpsych.theclinics.com
Evidence for the association between childhood trauma and psychosis is well supported
and continues to grow. In a recent sample of more than 4000 children, Croft and colleagues …
and continues to grow. In a recent sample of more than 4000 children, Croft and colleagues …
The role of cytokines in the pathogenesis of schizophrenia
B Dawidowski, A Górniak, P Podwalski… - Journal of Clinical …, 2021 - mdpi.com
Schizophrenia is a chronic mental illness of unknown etiology. A growing and compelling
body of evidence implicates immunologic dysfunction as the key element in its …
body of evidence implicates immunologic dysfunction as the key element in its …
Cytokines and C-reactive protein alterations with respect to cognitive impairment in schizophrenia and bipolar disorder: a systematic review
Background The aim of this article was to perform a systematic review of studies
investigating the association between peripheral levels of cytokines and C-reactive protein …
investigating the association between peripheral levels of cytokines and C-reactive protein …
Childhood adversity and psychosis: a systematic review of bio-psycho-social mediators and moderators
L Sideli, RM Murray, A Schimmenti, M Corso… - Psychological …, 2020 - cambridge.org
The association between childhood adversity (CA) and psychosis has been extensively
investigated in recent years. An increasing body of research has also focused on the …
investigated in recent years. An increasing body of research has also focused on the …