Advances in early breast cancer risk profiling: from histopathology to molecular technologies

C Pescia, E Guerini-Rocco, G Viale, N Fusco - Cancers, 2023 - mdpi.com
Simple Summary Risk stratification for early breast cancer (BC) is extremely relevant for
tailoring clinical decisions but challenging due to the absence of comprehensive guidelines …

Unveiling the immune microenvironment's role in breast cancer: A glimpse into promising frontiers

A Kotsifaki, N Alevizopoulos, V Dimopoulou… - International Journal of …, 2023 - mdpi.com
Breast cancer (BC), one of the most widespread and devastating diseases affecting women
worldwide, presents a significant public health challenge. This review explores the emerging …

Early Breast Cancer Risk Assessment: Integrating Histopathology with Artificial Intelligence

M Ivanova, C Pescia, D Trapani, K Venetis… - Cancers, 2024 - mdpi.com
Simple Summary Risk assessment in early breast cancer is critical for clinical decisions, but
defining risk categories poses a significant challenge. The integration of conventional …

Application of novel transcription factor machine learning model and targeted drug combination therapy strategy in triple negative breast cancer

J Pang, H Li, X Zhang, Z Luo, Y Chen, H Zhao… - International Journal of …, 2023 - mdpi.com
Transcription factors (TFs) have been shown to play a key role in the occurrence and
development of tumors, including triple-negative breast cancer (TNBC), with a worse …

Next-generation biomarkers for prognostic and potential therapeutic enhancement in Triple negative breast cancer

R Banerjee, I Maitra, T Bhattacharya… - Critical Reviews in …, 2024 - Elsevier
Triple-negative breast carcinoma (TNBC) is one of the most challenging subtypes of breast
carcinoma and it has very limited therapeutic options as it is highly aggressive. The …

Peptide-Modified Cyclodextrin-Based Nanosystem for Co-Delivery of Celastrol and siPD-L1 to Tumors

D Wang, T Zhang, Y Hu, Y Luo, Y Li… - ACS Applied Nano …, 2024 - ACS Publications
Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with high
immunogenicity. In this study, we developed a peptide-modified cyclodextrin-based …

PD-L1 testing in metastatic triple-negative breast cancer: Interobserver and interplatform reproducibility of CE-IVD assays for CPS and IC scores

M Ivanova, C Frascarelli, B Cerbelli, MG Pignataro… - Human Pathology, 2024 - Elsevier
PD-L1 test is recommended in different types of tumors to select patients eligible for immune
checkpoint inhibitors (ICI) therapy. Several factors make this test challenging in metastatic …

Mismatch repair protein deficiency in triple-negative breast carcinomas

B Maraqa, M Al-Ashhab, H Zughaier… - Journal of …, 2024 - journals.sagepub.com
Background Breast cancer, particularly triple-negative breast cancer (TNBC), poses a
significant global health burden. Chemotherapy was the mainstay treatment for TNBC …

Triple Negative Breast Cancer (TNBC): Cannabis sativa-Role of Phytocannabinoids

RB Malabadi, KP Kolkar, MR Sadiya… - World Journal of …, 2024 - wjbphs.com
This review paper highlights the role of phytocannabinoids in controlling triple-negative
breast cancer (TNBC). Triple-negative breast cancer (TNBC) is a specific subtype of breast …