MicroRNAs in allergy and asthma

A Rebane, CA Akdis - Current allergy and asthma reports, 2014 - Springer
Abstract microRNAs (miRNAs) are short, single-stranded RNA molecules that function
together with the partner proteins and cause degradation of target mRNAs or inhibit their …

Functionalized extracellular vesicles as advanced therapeutic nanodelivery systems

M Lu, H Xing, Z Xun, T Yang, X Zhao, C Cai… - European Journal of …, 2018 - Elsevier
Extracellular vesicles (EVs) are membrane enclosed vesicles that are shed by almost all cell
types, and play a fundamental role in cell-to-cell communication. The discovery that EVs are …

Exposure of Keratinocytes to Candida Albicans in the Context of Atopic Milieu Induces Changes in the Surface Glycosylation Pattern of Small Extracellular Vesicles …

A Kobiela, JE Frackowiak, A Biernacka… - Frontiers in …, 2022 - frontiersin.org
Candida albicans (C. albicans) infection is a potential complication in the individuals with
atopic dermatitis (AD) and can affect clinical course of the disease. Here, using primary …

Exosomes in neurologic and psychiatric disorders

I Tsilioni, S Panagiotidou, TC Theoharides - Clinical therapeutics, 2014 - Elsevier
Purposes The purposes of this review were to discuss the role of exosomes in neurologic
and psychiatric diseases and to propose future therapeutic approaches. Methods PubMed …

Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles as novel cell-free therapy for treatment of autoimmune disorders

FR Kahmini, S Shahgaldi - Experimental and Molecular Pathology, 2021 - Elsevier
Over the past decades, new light has been shed on the efficiency of Mesenchymal Stem
Cells (MSCs) in the treatment of autoimmune diseases. The therapeutic functions of MSCs …

Cellular delivery of RNA nanoparticles

L Parlea, A Puri, W Kasprzak, E Bindewald… - Therapeutic RNA …, 2021 - taylorfrancis.com
RNA nanostructures can be programmed to exhibit defined sizes, shapes and
stoichiometries from naturally occurring or de novo designed RNA motifs. These constructs …

Cell-derived exosomes as promising carriers for drug delivery and targeted therapy

X Wang, H Zhang, H Yang, M Bai… - Current cancer drug …, 2018 - ingentaconnect.com
Exosomes are small vesicles that are secreted by various types of cells, known to mediate
signal transduction between cells. During recent years, novel carriers for the delivery of …

Free extracellular miRNA functionally targets cells by transfecting exosomes from their companion cells

K Bryniarski, W Ptak, E Martin, K Nazimek… - PLoS …, 2015 - journals.plos.org
Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous
hapten application produce a suppressive component that inhibits the action of the effector T …

Associations between maternal lifetime stressors and negative events in pregnancy and breast milk-derived extracellular vesicle microRNAs in the programming of …

AK Bozack, E Colicino, R Rodosthenous… - Epigenetics, 2021 - Taylor & Francis
Maternal stress is associated with adverse child health. Breast milk microRNAs
encapsulated in extracellular vesicles (EVs) are involved in mother-infant biochemical …

Epigenome-modifying tools in asthma

PO Brook, MM Perry, IM Adcock, AL Durham - Epigenomics, 2015 - Taylor & Francis
Asthma is a chronic disease which causes recurrent breathlessness affecting 300 million
people worldwide of whom 250,000 die annually. The epigenome is a set of heritable …