Polycystic ovary syndrome (PCOS) is a common infertility disorder affecting a significant
proportion of the global population. It is the main cause of anovulatory infertility in women …

Most complex trait-associated variants are located in non-coding regulatory regions of the
genome, where they have been shown to disrupt transcription factor (TF)-DNA binding …

Notch signaling regulates a vast array of crucial developmental processes. It is therefore not
surprising that mutations in genes encoding Notch receptors or ligands lead to a variety of …

Abstract Background Transversions (Tv's) are more likely to alter the amino acid sequence
of proteins than transitions (Ts's), and local deviations in the Ts: Tv ratio are indicative of …

Alu are high copy number interspersed repeats that have accumulated near genes during
primate and human evolution. They are a pervasive source of structural variation in modern …

Gestational diabetes mellitus (GDM) is defined as abnormal glucose tolerance with onset or
first recognition during pregnancy. Women with a history of GDM are at long-term risk for …

Approximately 50 million people have epilepsy, making it the most common chronic and
severe neurological disease worldwide, with increased risk of mortality and psychological …

Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder affecting females in
their reproductive age. The early diagnosis of PCOS is complicated and complex due to …

Clinical studies of non-communicable diseases identify multimorbidities that suggest a
common set of predisposing factors. Despite the fact that humans have~ 24,000 genes, we …

There are substantial differences, or variation, between humans in aggression, with its
molecular genetic basis mostly unknown. This review summarizes knowledge on the genetic …