A systematic review of multimodal brain age studies: Uncovering a divergence between model accuracy and utility

RJ Jirsaraie, AJ Gorelik, MM Gatavins, DA Engemann… - Patterns, 2023 - cell.com
Brain aging is a complex, multifaceted process that can be challenging to model in ways that
are accurate and clinically useful. One of the most common approaches has been to apply …

Brain asymmetries from mid-to late life and hemispheric brain age

M Korbmacher, D van der Meer, D Beck… - Nature …, 2024 - nature.com
The human brain demonstrates structural and functional asymmetries which have
implications for ageing and mental and neurological disease development. We used a set of …

Prediction of brain age using structural magnetic resonance imaging: A comparison of accuracy and test–retest reliability of publicly available software packages

RP Dörfel, JM Arenas‐Gomez, PM Fisher… - Human Brain …, 2023 - Wiley Online Library
Brain age prediction algorithms using structural magnetic resonance imaging (MRI) aim to
assess the biological age of the human brain. The difference between a person's …

The effect of weight loss following 18 months of lifestyle intervention on brain age assessed with resting-state functional connectivity

G Levakov, A Kaplan, AY Meir, E Rinott, G Tsaban… - ELife, 2023 - elifesciences.org
Background: Obesity negatively impacts multiple bodily systems, including the central
nervous system. Retrospective studies that estimated chronological age from neuroimaging …

Bio-psycho-social factors' associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants

M Korbmacher, TP Gurholt, AMG de Lange… - Frontiers in …, 2023 - frontiersin.org
Brain age refers to age predicted by brain features. Brain age has previously been
associated with various health and disease outcomes and suggested as a potential …

Considerations on brain age predictions from repeatedly sampled data across time

M Korbmacher, MY Wang, R Eikeland… - Brain and …, 2023 - Wiley Online Library
Introduction Brain age, the estimation of a person's age from magnetic resonance imaging
(MRI) parameters, has been used as a general indicator of health. The marker requires …

The alteration of cortical microstructure similarity in drug-resistant epilepsy correlated with mTOR pathway genes

H Cao, P Wei, Y Huang, N Wang, LA Guo, X Fan… - …, 2023 - thelancet.com
Background Drug-resistant epilepsy (DRE) is associated with distributed laminar disruptions
due to cytoarchitectonic pathologies, which may be characterized by multimodal MRI …

Brain age has limited utility as a biomarker for capturing fluid cognition in older individuals

A Tetereva, N Pat - Elife, 2024 - elifesciences.org
One well-known biomarker candidate that supposedly helps capture fluid cognition is Brain
Age, or a predicted value based on machine-learning models built to predict chronological …

Inter-site generalizability of EEG based age prediction algorithms in the preterm infant

NJ Stevenson, T Nordvik, CN Espeland… - Physiological …, 2023 - iopscience.iop.org
Objective. To overcome the effects of site differences in EEG-based brain age prediction in
preterm infants. Approach. We used a'bag of features' with a combination function estimated …

Fiber Tract Shape Measures Inform Prediction of Non-Imaging Phenotypes

W Liu, Y Chen, C Ye, N Makris, Y Rathi, W Cai… - arXiv preprint arXiv …, 2023 - arxiv.org
Neuroimaging measures of the brain's white matter connections can enable the prediction of
non-imaging phenotypes, such as demographic and cognitive measures. Existing works …