Cerebrospinal fluid biomarkers in patients with unipolar depression compared with healthy control individuals: a systematic review and meta-analysis

IV Mousten, NV Sørensen, RHB Christensen… - JAMA …, 2022 - jamanetwork.com
Importance Depression has been associated with alterations in neurotransmitters,
hormones, and inflammatory and neurodegenerative biomarkers, and biomarkers quantified …

Major depressive disorder

RH Belmaker, G Agam - New England Journal of Medicine, 2008 - Mass Medical Soc
This review of major depressive disorder is a comprehensive account of the genetic,
biochemical, and neurophysiological changes that have been implicated in the disorder. No …

New approaches to antidepressant drug discovery: beyond monoamines

O Berton, EJ Nestler - Nature Reviews Neuroscience, 2006 - nature.com
All available antidepressant medications are based on serendipitous discoveries of the
clinical efficacy of two classes of antidepressants more than 50 years ago. These tricyclic …

HIV infection and depression

S Arseniou, A Arvaniti… - Psychiatry and clinical …, 2014 - Wiley Online Library
Major depression is highly prevalent among HIV‐positive patients (HIV pp). The prevalence
of depression ranges between 18% and 81%, depending on the population studied and the …

The thyroid‐brain interaction in thyroid disorders and mood disorders

M Bauer, T Goetz, T Glenn… - Journal of …, 2008 - Wiley Online Library
Thyroid hormones play a critical role in the metabolic activity of the adult brain, and
neuropsychiatric manifestations of thyroid disease have long been recognised. However, it …

The role of oxidative stress in depressive disorders

T Maria Michel, D Pulschen… - Current pharmaceutical …, 2012 - ingentaconnect.com
Studies of the World Health Organization suggest that in the year 2020, depressive disorder
will be the illness with the highest burden of disease. Especially unipolar depression is the …

Topologically convergent and divergent structural connectivity patterns between patients with remitted geriatric depression and amnestic mild cognitive impairment

F Bai, N Shu, Y Yuan, Y Shi, H Yu, D Wu… - Journal of …, 2012 - Soc Neuroscience
Alzheimer's disease (AD) can be conceptualized as a disconnection syndrome. Both
remitted geriatric depression (RGD) and amnestic mild cognitive impairment (aMCI) are …

[HTML][HTML] Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression

A Sequeira, F Mamdani, C Ernst, MP Vawter… - PloS one, 2009 - journals.plos.org
Background Most studies investigating the neurobiology of depression and suicide have
focused on the serotonergic system. While it seems clear that serotonergic alterations play a …

The medical management of depression

JJ Mann - New England Journal of Medicine, 2005 - Mass Medical Soc
The Medical Management of Depression | New England Journal of Medicine Skip to main content
The New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

The effects of psychotherapy on neural responses to rewards in major depression

GS Dichter, JN Felder, C Petty, J Bizzell, M Ernst… - Biological …, 2009 - Elsevier
BACKGROUND: Unipolar major depressive disorder (MDD) is characterized by anomalous
neurobiological responses to pleasant stimuli, a pattern that may be linked to symptoms of …