Chimeric antigen receptor-modified T (CAR-T) are genetically engineered cells to express
tumor-specific antigens revolutionizing the treatment of hematologic malignancies. The …

Simple Summary With around 15 kD molecular weight, VHHs are considered the smallest
antigen-binding fragments. Based on their unique properties, VHHs have broad application …

HLA‐G is considered as an immune checkpoint protein and a tumor‐associated antigen. In
the previous work, it is reported that CAR‐NK targeting of HLA‐G can be used to treat certain …

Background: B7H3 is a co-stimulatory molecule for immune reactions found on the surface
of tumor cells in a wide variety of tumors. Preclinical and clinical studies have reported it as a …

Simple Summary Chimeric antigen receptor T (CAR-T) therapy has revolutionized cancer
immunotherapy by inducing a durable response in patients with acute lymphoblastic …

Osteosarcoma is a malignant tumor originating from bone tissue that progresses rapidly and
has a poor patient prognosis. Immunotherapy has shown great potential in the treatment of …

Simple Summary We evaluated a novel proprietary murine B7-H3 antibody 8H8 for flow
cytometric analyses of patients with acute myeloid leukemia (AML). The results showed …

Abstract Cluster of differentiation 47 (CD47) is a transmembrane protein that is widely and
moderately expressed on the surface of various cells and can have an essential role in …

Choroid plexus tumors (CPT) are believed to originate from outgrowths of the choroid
plexus. Despite their broad spectrum of symptoms, invasive nature, and prognosis, most …

Abstract B7-H3 (CD276), an immune checkpoint protein of the B7 family, exhibits significant
upregulation in solid tumors and hematologic malignancies, exerting a crucial role in their …