Oral versus intravenous steroids for treatment of relapses in multiple sclerosis

JM Burton, PW O'Connor, M Hohol… - Cochrane Database of …, 2012 - cochranelibrary.com
Oral versus intravenous steroids for treatment of relapses in multiple sclerosis - Burton, JM - 2012
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[HTML][HTML] Multiple sclerosis review

MM Goldenberg - Pharmacy and therapeutics, 2012 - ncbi.nlm.nih.gov
Multiple sclerosis (MS) is a chronic autoimmune, inflammatory neurological disease of the
central nervous system (CNS). 1, 2 MS attacks the myelinated axons in the CNS, destroying …

Corticosteroids in the management of acute multiple sclerosis exacerbations

I Smets, L Van Deun, C Bohyn, V Van Pesch… - Acta Neurologica …, 2017 - Springer
Multiple sclerosis (MS) is an autoimmune, inflammatory demyelinating disease of the central
nervous system characterized in the majority of the patients by a relapsing-remitting disease …

Intravenous methylprednisolone pulses in hospitalised patients with severe COVID-19 pneumonia: a double-blind, randomised, placebo-controlled trial

C Salvarani, M Massari, M Costantini… - European …, 2022 - Eur Respiratory Soc
Rationale Pulse glucocorticoid therapy is used in hyperinflammation related to coronavirus
disease 2019 (COVID-19). We evaluated the efficacy and safety of pulse intravenous …

Randomised trial of oral and intravenous methylprednisolone in acute relapses of multiple sclerosis

D Barnes, RAC Hughes, RW Morris, O Wade-Jones… - The Lancet, 1997 - thelancet.com
Background An intravenous rather than oral course of methylprednisolone is often
prescribed for treating acute relapses in multiple sclerosis (MS) despite the lack of evidence …

EFNS guideline on treatment of multiple sclerosis relapses: report of an EFNS task force on treatment of multiple sclerosis relapses

F Sellebjerg, D Barnes, G Filippini… - European journal of …, 2005 - Wiley Online Library
Relapses, exacerbations or attacks of multiple sclerosis are the dominating feature of
relapsing‐remitting multiple sclerosis (MS), but are also observed in patients with secondary …

Pulse steroid therapy

A Sinha, A Bagga - The Indian Journal of Pediatrics, 2008 - Springer
Intravenous supra-pharmacological doses of corticosteroids are used in various
inflammatory and autoimmune conditions because they are cumulatively less toxic than …

High-dose methylprednisolone therapy in multiple sclerosis induces apoptosis in peripheral blood leukocytes

VI Leussink, S Jung, U Merschdorf… - Archives of …, 2001 - jamanetwork.com
Background Apoptosis is supposed to contribute to the elimination of T cells from the
inflamed central nervous system in the natural disease course of multiple sclerosis (MS). In …

A meta-analysis of methylprednisolone in recovery from multiple sclerosis exacerbations

DM Miller, B Weinstock-Guttman… - Multiple Sclerosis …, 2000 - journals.sagepub.com
Despite recent advances in multiple sclerosis treatment, patients experience relapses for
which standard treatment remains glucocorticosteroids (GCS). However, there is limited …

[PDF][PDF] Multiple sclerosis: advances in understanding, diagnosing, and treating the underlying disease

RJ Fox, F Bethoux, MD Goldman… - Cleveland Clinic journal …, 2006 - cdn.mdedge.com
■ ABSTRACT Recent advances in our understanding of the diagnosis, imaging, pathology,
and clinical monitoring of multiple sclerosis (MS) have significantly increased our ability to …