Nanodiagnostics to face SARS-CoV-2 and future pandemics: From an idea to the market and beyond

G Rosati, A Idili, C Parolo, C Fuentes-Chust… - ACS …, 2021 - ACS Publications
The COVID-19 pandemic made clear how our society requires quickly available tools to
address emerging healthcare issues. Diagnostic assays and devices are used every day to …

Improved calibration of electrochemical aptamer-based sensors

AM Downs, J Gerson, KK Leung, KM Honeywell… - Scientific reports, 2022 - nature.com
Electrochemical aptamer-based (EAB) sensors support the real-time, high frequency
measurement of pharmaceuticals and metabolites in-situ in the living body, rendering them …

SARS-Cov-2 spike-S1 antigen test strip with high sensitivity endowed by high-affinity antibodies and brightly fluorescent QDs/silica nanospheres

S Tao, X Zhao, D Bao, X Liu, W Zhang… - … Applied Materials & …, 2023 - ACS Publications
The extensive research into developing novel strategies for detecting respiratory syndrome
coronavirus 2 (SARS-CoV-2) antigens in clinical specimens, especially the sensitive point-of …

C-MEMS-derived glassy carbon electrochemical biosensors for rapid detection of SARS-CoV-2 spike protein

N Mandal, R Mitra, B Pramanick - Microsystems & Nanoengineering, 2023 - nature.com
Abstract According to a World Health Organization (WHO) report, the world has experienced
more than 766 million cases of positive SARS-CoV-2 infection and more than 6.9 million …

Consensus receptor-binding domain-targeted aptamer selection and designing of a photonic crystal-decorated aptasensor for SARS-CoV-2

G Murtaza, AS Rizvi, M Xue, L Qiu, Z Meng - Analytical chemistry, 2022 - ACS Publications
The frequent emergence of variants of concern (VOC) of SARS-CoV-2 necessitates a
sensitive and all-inclusive detection platform that remains viable despite the virus mutations …

[HTML][HTML] Development of a simple gelatin-based sensing platform for the sensitive label-free impedimetric detection of SARS-CoV-2

A Lobato, M Šubic, T Romih, L Žibret, D Metarapi… - Electrochimica …, 2023 - Elsevier
The persistent nature of the SARS-CoV-2 virus, characterized by its large-scale periodical
recurrence and high infectivity, has imposed an increasing demand for rapid and frequent …

Aptamers for SARS‐CoV‐2: Isolation, Characterization, and Diagnostic and Therapeutic Developments

R Amini, Z Zhang, J Li, J Gu, JD Brennan… - Analysis & …, 2022 - Wiley Online Library
The SARS‐CoV‐2 virus and COVID‐19 pandemic continue to demand effective diagnostic
and therapeutic solutions. Finding these solutions requires highly functional molecular …

Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices

C Parolo, A Idili, J Heikenfeld, KW Plaxco - Lab on a Chip, 2023 - pubs.rsc.org
Recent years have seen continued expansion of the functionality of lab on a chip (LOC)
devices. Indeed LOCs now provide scientists and developers with useful and versatile …

SCORe: SARS-CoV-2 omicron variant RBD-binding DNA aptamer for multiplexed rapid detection and pseudovirus neutralization

LF Yang, N Kacherovsky, J Liang, SJ Salipante… - Analytical …, 2022 - ACS Publications
During the COVID-19 (coronavirus disease 2019) pandemic, several SARS-CoV-2 variants
of concern emerged, including the Omicron variant, which has enhanced infectivity and …

Highly sensitive aptasensor for the detection of SARS-CoV-2-RBD using aptamer-gated methylene blue@ mesoporous silica film/laser engraved graphene electrode

MA Tabrizi, P Acedo - Biosensors and Bioelectronics, 2022 - Elsevier
Herein, an aptasensor was designed to detect the receptor-binding domain of severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2-RBD) based on the encapsulation of the …