Non-invasive early molecular detection of gastric cancers

H Yamamoto, Y Watanabe, Y Sato, T Maehata, F Itoh - Cancers, 2020 - mdpi.com
Simple Summary This paper reviewed an update on the molecular detection of gastric
cancers, focusing on various diagnostic approaches, including nonblood analytes …

Clinical evaluation of a novel molecular diagnosis kit for detecting Helicobacter pylori and clarithromycin‐resistant using intragastric fluid

M Tsuda, Y Watanabe, R Oikawa, R Watanabe… - …, 2022 - Wiley Online Library
Background Although there are many Helicobacter pylori (H. pylori) diagnostic methods, the
culture and antibiotic susceptibility test is an important method for selecting the most …

Cancer‐related genetic variants of Helicobacter pylori strains determined using gastric wash‐based whole‐genome analysis with single‐molecule real‐time …

Y Watanabe, R Oikawa, Y Kodaka… - … Journal of Cancer, 2021 - Wiley Online Library
Helicobacter pylori (H. pylori) are a primary factor in the pathogenesis of gastric cancer (GC);
GC ranks third among cancer‐related mortality. A clear understanding of the H. pylori …

Impact of mixed‐infection rate of clarithromycin‐susceptible and clarithromycin‐resistant Helicobacter pylori strains on the success rate of clarithromycin‐based …

M Tsuda, Y Watanabe, R Oikawa, R Watanabe… - …, 2024 - Wiley Online Library
Background Clarithromycin (CAM) resistance is a major contributor to the failure to eradicate
Helicobacter pylori (H. pylori). The mixed‐infection ratio of CAM‐susceptible and CAM …

Combination of artificial intelligence‐based endoscopy and miR148a methylation for gastric indefinite dysplasia diagnosis

Y Watanabe, R Oikawa, S Agawa… - Journal of Clinical …, 2022 - Wiley Online Library
Abstract Background and Aim Gastrointestinal endoscopy and biopsy‐based pathological
findings are needed to diagnose early gastric cancer. However, the information of biopsy …

Quantitative analysis of single‐nucleotide polymorphisms by pyrosequencing with di‐base addition

D Pu, R Pan, W Liu, P Xiao - Electrophoresis, 2017 - Wiley Online Library
We have developed and validated a novel method for quantitative detection of SNPs by
using pyrosequencing with di‐base addition (PDBA). Based on the principle that the signal …

[HTML][HTML] 幽门螺杆菌抗生素耐药相关菌体因素的研究进展

王丹, 宫月华, 袁媛 - 世界华人消化杂志, 2016 - wjgnet.com
幽门螺杆菌(Helicobacter pylori, H. pylori) 感染是最广泛的慢性细菌感染,
与许多疾病的发生发展密切相关. 近年来, 随着根除治疗的不断应用, H. pylori …

Enrichment of Helicobacter pylori mutant strains after eradication therapy analyzed by gastric wash–based quantitative pyrosequencing

R Oikawa, Y Watanabe, S Miyamoto, Y Sato… - Tumor …, 2017 - journals.sagepub.com
The eradication of Helicobacter pylori reduces the risk of gastric cancer. A clear
understanding of the factors underlying mixed infection with multiple clarithromycin …

Mouthwash-Based Highly Sensitive Pyro-Genotyping for Nine Sexually Transmitted Human Papilloma Virus Genotypes

Y Watanabe, Y Seto, R Oikawa, T Nakazawa… - International Journal of …, 2020 - mdpi.com
Human papillomavirus (HPV) is a common sexually transmitted infection worldwide, which
spreads via contact with infected genital, anal, and oral/pharyngeal areas (oral sex) owing to …

胃発癌リスクマーカーとしての同一症例における胃内ピロリ菌複数種の混在比検討

及川律子, 渡邊嘉行, 宮本秀一, 小野尚子… - 日本分子腫瘍マーカー …, 2017 - jstage.jst.go.jp
23SrRNA がピロリ菌に特異的な遺伝子配列の部位をバイオインフォマティクス解析により確認した
後, 同部位にプライマーを設計しパイロシークエンス法を用いて複数種の菌混在比を定量的に解析 …