Abstract Cucinotta, FA, Pluth, JM, Anderson, JA, Harper, JV and O'Neill, P. Biochemical
Kinetics Model of DSB Repair and Induction of γ-H2AX Foci by Non-homologous End …

Living organisms persist by virtue of complex interactions among many components
organized into dynamic, environment-responsive networks that span multiple scales and …

This text presents the modeling, analysis, and design methods for systems biology. It
discusses how to examine experimental data to learn about mathematical models, develop …

Aging is a biological process characterized by the progressive functional decline of many
interrelated physiological systems. In particular, aging is associated with the development of …

Considering the fluid nature of nano breakthroughs—and the delicate balance between
benefits and consequences as they apply to medicine—readers at all levels require a …

The significance of regular path queries (RPQs) on graph-like data structures has grown
steadily over the past decade. RPQs are, often in restricted forms, part of graph-oriented …

Systems Biology has a mission that puts it at odds with traditional paradigms of physics and
molecular biology, such as the simplicity requested by Occam's razor and minimum …

Integrative biology is a label frequently used to describe various forms of cross-disciplinary
and multitaxon research. The term is ill defined, but in fact it does rely on principles that are …

A recent initiative named 'Crops in silico'proposes that multi-scale models 'have the potential
to fill in missing mechanistic details and generate new hypotheses to prioritize directed …

Reaction rates or metabolic fluxes reflect the integrated phenotype of genome, transcriptome
and proteome interactions, including regulation at all levels of the cellular hierarchy …