Diabetes, COVID‐19, and questions unsolved

F D'Souza, R Buzzetti, P Pozzilli - … /Metabolism Research and …, 2023 - Wiley Online Library
Recent evidence suggests a role for Diabetes Mellitus in adverse outcomes from COVID‐19
infection; yet the underlying mechanisms are not clear. Moreover, attention has turned to …

Dynamical modelling of viral infection and cooperative immune protection in COVID-19 patients

Z Zhou, D Li, Z Zhao, S Shi, J Wu, J Li… - PLOS Computational …, 2023 - journals.plos.org
Once challenged by the SARS-CoV-2 virus, the human host immune system triggers a
dynamic process against infection. We constructed a mathematical model to describe host …

Inflammation propagation modeled as a reaction–diffusion wave

W El Hajj, N El Khatib, V Volpert - Mathematical Biosciences, 2023 - Elsevier
Inflammation is a physiological process aimed to protect the organism in various diseases
and injuries. This work presents a generic inflammation model based on the reaction …

Dynamic behaviors of a COVID-19 and influenza co-infection model with time delays and humoral immunity

AM Elaiw, RS Alsulami, AD Hobiny - Axioms, 2023 - mdpi.com
Co-infections with respiratory viruses were reported in hospitalized patients in several
cases. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A …

Modeling of Viral Infection with Inflammation

A Mozokhina, L Ait Mahiout, V Volpert - Mathematics, 2023 - mdpi.com
Viral infection spreads in cell culture or tissue as a reaction–diffusion wave. It is
characterized by three main parameters: virus replication number, R v, which determines …

A Mathematical Model Simulating the Adaptive Immune Response in Various Vaccines and Vaccination Strategies

Z Xu, J Song, H Zhang, Z Wei, D Wei, J Demongeot - medRxiv, 2023 - medrxiv.org
Vaccination is the most effective measure for preventing infectious diseases. Developing an
appropriate mathematical model facilitates quantitative research into the activation of …

Evaluation of CoronaVac and CoviShield Vaccines on SARS-CoV-2 Infection in Healthcare Workers in Salvador, Brazil

JE Patiño Escarcina, FJ Souza, AKCV Da Silva… - COVID, 2023 - mdpi.com
The emergence and rapid spread of the SARS-CoV-2 Gamma variant in Brazil have raised
concerns about SARS-CoV-2 vaccines' neutralizing capacity and viral load impact. Our …

Topological data analysis of antibody dynamics of severe and non-severe patients with COVID-19

R Blanco-Rodríguez, F Ordoñez-Jiménez… - Mathematical …, 2023 - Elsevier
The COVID-19 pandemic is a significant public health threat with unanswered questions
regarding the immune system's role in the disease's severity level. Here, based on antibody …

Dynamic Modeling of Antibody Repertoire Reshaping in Response to Viral Infections

Z Xu, J Xu, J Song, H Zhang, D Wei, Q Zeng, K Bryant - bioRxiv, 2024 - biorxiv.org
For many years, researchers have emphasized the production of high-affinity specific
antibodies by hosts during viral infections. However, this has made it challenging for …

Analysis of Humoral Immunity SARS-CoV-2 Infection Model with ACE2 Receptor and Latent Phase

AM Elaiw, AS Alsulami, AD Hobiny - Contemporary Mathematics, 2024 - ojs.wiserpub.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is RNA virus which causes
the coronavirus disease 2019 (COVID-19). SARS-CoV-2 infects the epithelial (target) cells …