The use of circulating biomarkers for heart failure (HF) is engrained in contemporary
cardiovascular practice and provides objective information about various pathophysiological …

Aims Ketone bodies (KB) are an important alternative metabolic fuel source for the
myocardium. Experimental and human investigations suggest that KB may have protective …

Objectives The purpose of this study was to determine the frequency of unexpectedly low
natriuretic peptide (NP) levels in a clinical population. Background Higher NP …

Importance It is unclear to what extent insulin resistance is associated with N-terminal pro-B-
type natriuretic peptide (NT-proBNP) in the general population after accounting for body …

Obesity-associated comorbidities include non-alcoholic fatty liver disease, Type 2 diabetes,
and cardiovascular disease. These diseases are associated with accumulation of lipids in …

There are few proven therapies for heart failure with preserved ejection fraction (HFpEF).
The lack of therapies, along with increased recognition of the disorder and its underlying …

Obesity-related adipose tissue (AT) dysfunction, in particular subcutaneous AT (SCAT)
lipolysis, is characterized by catecholamine resistance and impaired atrial natriuretic peptide …

Natriuretic peptides are cardiac-derived hormones with a range of protective functions,
including natriuresis, diuresis, vasodilation, lusitropy, lipolysis, weight loss, and improved …

For many years, it has been recognized that hypertension tends to cluster with various
anthropometric and metabolic abnormalities including abdominal obesity, elevated …

Important differences in comorbidities and clinical characteristics exist between women and
men with heart failure (HF). In particular, differences in the kinetics of biological circulating …