S Julius, SE Kjeldsen, M Weber, HR Brunner, S Ekman… - The Lancet, 2004 - thelancet.com
Summary Background The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial was designed to test the hypothesis that for the same blood-pressure control, valsartan …
Accelerated cardiovascular disease is a frequent complication of renal disease. Chronic kidney disease promotes hypertension and dyslipidemia, which in turn can contribute to the …
SC Smith Jr, J Allen, SN Blair, RO Bonow, LM Brass… - Circulation, 2006 - Am Heart Assoc
• Ask about tobacco use status at every visit. I (B)• Advise every tobacco user to quit. I (B)• Assess the tobacco user's willingness to quit. I (B)• Assist by counseling and developing a …
KS Jering, B Claggett, MA Pfeffer… - European journal of …, 2021 - Wiley Online Library
Aims Patients surviving an acute myocardial infarction (AMI) are at risk of developing symptomatic heart failure (HF) or premature death. We hypothesized that …
IY Elgendy, D Mahtta, CJ Pepine - Circulation research, 2019 - Am Heart Assoc
Patients with heart failure (HF) syndromes have been categorized as those with reduced ejection fraction (EF) or preserved EF (HFpEF), and ischemia plays a key role in both types …
NS Anavekar, JJV McMurray… - … England Journal of …, 2004 - Mass Medical Soc
Background The presence of coexisting conditions has a substantial effect on the outcome of acute myocardial infarction. Renal failure is associated with one of the highest risks, but …
MA Konstam, JD Neaton, K Dickstein, H Drexler… - The Lancet, 2009 - thelancet.com
Summary Background Angiotensin-receptor blockers (ARBs) are effective treatments for patients with heart failure, but the relation between dose and clinical outcomes has not been …
JR Erickson, AJ Mei-ling, X Guan, W Kutschke, J Yang… - Cell, 2008 - cell.com
Summary Calcium/calmodulin (Ca 2+/CaM)-dependent protein kinase II (CaMKII) couples increases in cellular Ca 2+ to fundamental responses in excitable cells. CaMKII was …
NAVIGATOR Study Group - New England Journal of Medicine, 2010 - Mass Medical Soc
Background It is not known whether drugs that block the renin–angiotensin system reduce the risk of diabetes and cardiovascular events in patients with impaired glucose tolerance …