Topics in herpesvirus genomics and evolution

DJ McGeoch, FJ Rixon, AJ Davison - Virus research, 2006 - Elsevier
Herpesviruses comprise an abundant, widely distributed group of large DNA viruses of
humans and other vertebrates, and overall are among the most extensively studied large …

Evolution of the herpesviruses

AJ Davison - Veterinary microbiology, 2002 - Elsevier
The complete genome sequences of 26 herpesvirus species, some represented by more
than one strain, are currently deposited in the public databases. Their combined length …

[HTML][HTML] Specific capture and whole-genome sequencing of viruses from clinical samples

DP Depledge, AL Palser, SJ Watson, IYC Lai, ER Gray… - PloS one, 2011 - journals.plos.org
Whole genome sequencing of viruses directly from clinical samples is integral for
understanding the genetics of host-virus interactions. Here, we report the use of sample …

Kaposi's sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays

RG Jenner, MM Alba, C Boshoff, P Kellam - Journal of virology, 2001 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV; human herpesvirus 8) is associated with
three human tumors, Kaposi's sarcoma, primary effusion lymphoma (PEL), and multicentric …

Molecular genetics of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) epidemiology and pathogenesis

LA Dourmishev, AL Dourmishev… - Microbiology and …, 2003 - Am Soc Microbiol
Kaposi's sarcoma had been recognized as unique human cancer for a century before it
manifested as an AIDS-defining illness with a suspected infectious etiology. The discovery of …

[HTML][HTML] The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes

T Günther, A Grundhoff - PLoS pathogens, 2010 - journals.plos.org
Herpesvirus latency is generally thought to be governed by epigenetic modifications, but the
dynamics of viral chromatin at early timepoints of latent infection are poorly understood …

Kaposi sarcoma herpesvirus pathogenesis

G Mariggio, S Koch, TF Schulz - … Transactions of the …, 2017 - royalsocietypublishing.org
Kaposi sarcoma herpesvirus (KSHV), taxonomical name human gammaherpesvirus 8, is a
phylogenetically old human virus that co-evolved with human populations, but is now only …

KSHV: pathways to tumorigenesis and persistent infection

L Giffin, B Damania - Advances in virus research, 2014 - Elsevier
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8) is
the etiologic agent of Kaposi's sarcoma, primary effusion lymphoma, and multicentric …

KSHV vFLIP binds to IKK-γ to activate IKK

N Field, W Low, M Daniels, S Howell… - Journal of cell …, 2003 - journals.biologists.com
When expressed in heterologous cells, the viral FLIP protein (vFLIP) of Kaposi's-sarcoma-
associated herpesvirus (KSHV) has been reported both to block Fas-mediated apoptosis …

Kaposi Sarcoma-associated Herpesvirus: mechanisms of oncogenesis

TF Schulz, E Cesarman - Current opinion in virology, 2015 - Elsevier
Highlights•KSHV/HHV8 causes three human diseases: Kaposi Sarcoma, Primary Effusion
Lymphoma and the plasma cell variant of Multicentric Castleman Disease.•These occur …