[HTML][HTML] Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori

NR Salama, ML Hartung, A Müller - Nature Reviews Microbiology, 2013 - nature.com
The bacterial pathogen Helicobacter pylori has co-evolved with humans and colonizes
approximately 50% of the human population, but only causes overt gastric disease in a …

Pathogenesis of Helicobacter pylori Infection

JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - Am Soc Microbiol
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies

P Oster, L Vaillant, E Riva, B McMillan, C Begka… - Gut, 2022 - gut.bmj.com
Objective In this study, we determined whether Helicobacter pylori (H. pylori) infection
dampens the efficacy of cancer immunotherapies. Design Using mouse models, we …

Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation

M von Köckritz-Blickwede, O Goldmann… - Blood, The Journal …, 2008 - ashpublications.org
These days it has been increasingly recognized that mast cells (MCs) are critical
components of host defense against pathogens. In this study, we have provided the first …

Helicobacter pylori Persistence: an Overview of Interactions between H. pylori and Host Immune Defenses

HMS Algood, TL Cover - Clinical microbiology reviews, 2006 - Am Soc Microbiol
Helicobacter pylori is a gram-negative bacterium that persistently colonizes more than half of
the global human population. In order to successfully colonize the human stomach, H. pylori …

[HTML][HTML] Mast cells in the skin: defenders of integrity or offenders in inflammation?

M Voss, J Kotrba, E Gaffal… - International Journal of …, 2021 - mdpi.com
Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions
that may even culminate in life-threatening anaphylactic shock syndromes. However …

Immunology of Helicobacter pylori: insights into the failure of the immune response and perspectives on vaccine studies

KT Wilson, JE Crabtree - Gastroenterology, 2007 - Elsevier
Helicobacter pylori infects the stomach of half of the human population worldwide and
causes chronic active gastritis, which can lead to peptic ulcer disease, gastric …

New and emerging roles for mast cells in host defence

W Dawicki, JS Marshall - Current opinion in immunology, 2007 - Elsevier
Mast cells are highly effective sentinel cells, found close to blood vessels and especially
common sites of potential infection, such as the skin, airways and gastrointestinal tract. Mast …

Differential inflammatory response to Helicobacter pylori infection: etiology and clinical outcomes

JR White, JA Winter, K Robinson - Journal of inflammation …, 2015 - Taylor & Francis
The bacterial pathogen Helicobacter pylori commonly colonizes the human gastric mucosa
during early childhood and persists throughout life. The organism has evolved multiple …

The inflammatory and immune response to Helicobacter pylori infection

K Robinson, RH Argent, JC Atherton - Best practice & research Clinical …, 2007 - Elsevier
Lifelong Helicobacter pylori infection and its associated gastric inflammation underlie peptic
ulceration and gastric carcinogenesis. The immune and inflammatory responses to H. pylori …