ATP-binding cassette efflux transporters and MDR in cancer

MS Pote, RN Gacche - Drug Discovery Today, 2023 - Elsevier
Highlights•The most common reason for the failure of the cancer treatment is the evolving
drug resistance.•The ABC transporters mainly P-gp, BCRP and MRP1 are responsible for …

Recent advances in nanomaterials-based targeted drug delivery for preclinical cancer diagnosis and therapeutics

H Tiwari, N Rai, S Singh, P Gupta, A Verma, AK Singh… - Bioengineering, 2023 - mdpi.com
Nano-oncology is a branch of biomedical research and engineering that focuses on using
nanotechnology in cancer diagnosis and treatment. Nanomaterials are extensively …

Precise Engineering of a Se/Te Nanochaperone for Reinvigorating Cancer Radio‐Immunotherapy

Y Chang, J Huang, S Shi, L Xu, H Lin… - Advanced …, 2023 - Wiley Online Library
Facilely synthesized nanoradiosensitizers with well‐controlled structure and
multifunctionality are greatly desired to address the challenges of cancer radiotherapy. In …

Biogenic selenium nanoparticles in biomedical sciences: properties, current trends, novel opportunities and emerging challenges in theranostic nanomedicine

MC Zambonino, EM Quizhpe, L Mouheb, A Rahman… - Nanomaterials, 2023 - mdpi.com
Selenium is an important dietary supplement and an essential trace element incorporated
into selenoproteins with growth-modulating properties and cytotoxic mechanisms of action …

SNPs in 3′ UTR miRNA target sequences associated with individual drug susceptibility

E Rykova, N Ershov, I Damarov… - International Journal of …, 2022 - mdpi.com
The complementary interaction of microRNAs (miRNAs) with their binding sites in the 3′
untranslated regions (3′ UTRs) of target gene mRNAs represses translation, playing a …

In situ, synthesis of chitosan fabricated tellurium nanoparticles for improved antimicrobial and anticancer applications

A Sathiyaseelan, X Zhang, J Lin, MH Wang - International Journal of …, 2024 - Elsevier
The emergence of antibiotic resistance has had a severe impact on human health and
economic burdens, drawing attention to the development of novel antimicrobial therapies …

Biosynthesis of Novel Tellurium Nanorods by Gayadomonas sp. TNPM15 Isolated from Mangrove Sediments and Assessment of Their Impact on Spore Germination …

MN Abd El-Ghany, SA Hamdi, SM Korany, RM Elbaz… - Microorganisms, 2023 - mdpi.com
The biosynthesis of nanoparticles using green technology is emerging as a cost-efficient,
eco-friendly and risk-free strategy in nanotechnology. Recently, tellurium nanoparticles …

[HTML][HTML] Selenomethionine in gelatin methacryloyl hydrogels: modulating ferroptosis to attenuate skin aging

J Sun, X Xie, Y Song, T Sun, X Liu, H Yuan, C Shen - Bioactive Materials, 2024 - Elsevier
During skin aging, the degeneration of epidermal stem cells (EpiSCs) leads to diminished
wound healing capabilities and epidermal disintegration. This study tackles this issue …

Role of antioxidant vitamins and other micronutrients on regulations of specific genes and signaling pathways in the prevention and treatment of cancer

OF Fagbohun, CR Gillies, KPJ Murphy… - International Journal of …, 2023 - mdpi.com
Cancer is an escalating global issue, with 19.3 million new cases and 9.9 million deaths in
2020. Therefore, effective approaches to prevent cancer are urgently required. Diet plays a …

[HTML][HTML] Epilepsy: Mitochondrial connections to the 'Sacred'disease

WH Moos, DV Faller, IP Glavas, I Kanara, K Kodukula… - Mitochondrion, 2023 - Elsevier
Over 65 million people suffer from recurrent, unprovoked seizures. The lack of validated
biomarkers specific for myriad forms of epilepsy makes diagnosis challenging. Diagnosis …