[HTML][HTML] HIV-1 infection and AIDS: consequences for the central nervous system

M Kaul, J Zheng, S Okamoto, HE Gendelman… - Cell Death & …, 2005 - nature.com
Infection with the human immunodeficiency virus-1 (HIV-1) can induce severe and
debilitating neurological problems that include behavioral abnormalities, motor dysfunction …

Pathogenesis of human immunodeficiency virus-induced neurological disease

AV Albright, SS Soldan, F González-Scarano - Journal of neurovirology, 2003 - Springer
Infection of the central nervous system by the type 1 human immunodeficiency virus (HIV-1)
commonly results in a number of neurological impairments known, in their most severe form …

HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration

K Zhang, GA McQuibban, C Silva, GS Butler… - Nature …, 2003 - nature.com
The mechanisms of neurodegeneration that result in human immunodeficiency virus (HIV)
type 1 dementia have not yet been identified. Here, we report that HIV-infected …

[HTML][HTML] Increased monocyte turnover from bone marrow correlates with severity of SIV encephalitis and CD163 levels in plasma

TH Burdo, C Soulas, K Orzechowski, J Button… - PLoS …, 2010 - journals.plos.org
Cells of the myeloid lineage are significant targets for human immunodeficiency virus (HIV)
in humans and simian immunodeficiency virus (SIV) in monkeys. Monocytes play critical …

Synergistic increases in intracellular Ca2+, and the release of MCP‐1, RANTES, and IL‐6 by astrocytes treated with opiates and HIV‐1 Tat

N El‐Hage, JA Gurwell, IN Singh, PE Knapp, A Nath… - Glia, 2005 - Wiley Online Library
Recent evidence suggests that injection drug users who abuse heroin are at increased risk
of CNS complications from human immunodeficiency virus (HIV) infection. Opiate drugs may …

Neurotoxicity of HIV-1 proteins gp120 and Tat in the rat striatum

AK Bansal, CF Mactutus, A Nath, W Maragos… - Brain research, 2000 - Elsevier
HIV-associated dementia complex is a serious disabling disease characterized by cognitive,
behavioral and motor dysfunction. Basal ganglia involvement in HIV-1 infection may be …

Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants

J Turchan, CB Pocernich, C Gairola, A Chauhan… - Neurology, 2003 - AAN Enterprises
Objective: To determine the role of oxidative stress in mediating HIV dementia and to identify
novel therapeutic compounds that may block this oxidative stress. Methods: Brain tissue …

[HTML][HTML] Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal …

A Chauhan, J Turchan, C Pocernich… - Journal of Biological …, 2003 - ASBMB
The human immunodeficiency virus (HIV)-Tat protein has been implicated in the
neuropathogenesis of HIV infection. However, its role in modulating astroglial-neuronal …

Schizophrenia and viral infection during neurodevelopment: a focus on mechanisms

BD Pearce - Molecular psychiatry, 2001 - nature.com
The task of defining schizophrenia pathogenesis has fascinated and frustrated researchers
for nearly a century. In recent years, unprecedented advances from diverse fields of study …

Oxidative stress, perturbed calcium homeostasis, and immune dysfunction in Alzheimer's disease

MP Mattson - Journal of neurovirology, 2002 - Taylor & Francis
Although Alzheimer's disease (AD) may not involve a transmissible agent, it does involve a
pathogenic process similar to that of transmissible prion disorders (both involve a protein …