Infection of the central nervous system by the type 1 human immunodeficiency virus (HIV-1) commonly results in a number of neurological impairments known, in their most severe form …
K Zhang, GA McQuibban, C Silva, GS Butler… - Nature …, 2003 - nature.com
The mechanisms of neurodegeneration that result in human immunodeficiency virus (HIV) type 1 dementia have not yet been identified. Here, we report that HIV-infected …
TH Burdo, C Soulas, K Orzechowski, J Button… - PLoS …, 2010 - journals.plos.org
Cells of the myeloid lineage are significant targets for human immunodeficiency virus (HIV) in humans and simian immunodeficiency virus (SIV) in monkeys. Monocytes play critical …
N El‐Hage, JA Gurwell, IN Singh, PE Knapp, A Nath… - Glia, 2005 - Wiley Online Library
Recent evidence suggests that injection drug users who abuse heroin are at increased risk of CNS complications from human immunodeficiency virus (HIV) infection. Opiate drugs may …
AK Bansal, CF Mactutus, A Nath, W Maragos… - Brain research, 2000 - Elsevier
HIV-associated dementia complex is a serious disabling disease characterized by cognitive, behavioral and motor dysfunction. Basal ganglia involvement in HIV-1 infection may be …
J Turchan, CB Pocernich, C Gairola, A Chauhan… - Neurology, 2003 - AAN Enterprises
Objective: To determine the role of oxidative stress in mediating HIV dementia and to identify novel therapeutic compounds that may block this oxidative stress. Methods: Brain tissue …
A Chauhan, J Turchan, C Pocernich… - Journal of Biological …, 2003 - ASBMB
The human immunodeficiency virus (HIV)-Tat protein has been implicated in the neuropathogenesis of HIV infection. However, its role in modulating astroglial-neuronal …
The task of defining schizophrenia pathogenesis has fascinated and frustrated researchers for nearly a century. In recent years, unprecedented advances from diverse fields of study …
MP Mattson - Journal of neurovirology, 2002 - Taylor & Francis
Although Alzheimer's disease (AD) may not involve a transmissible agent, it does involve a pathogenic process similar to that of transmissible prion disorders (both involve a protein …