The three-dimensional structure of chromatin regulates gene expression by facilitating
contacts between promoters and regulatory elements, demarcating regions of activity and …

In this paper, I introduce a Sequence-based Multiscale Model (SeqMM) for the biomolecular
data analysis. With the combination of spectral graph method, I reveal the essential …

Eukaryotic genomes replicate via the synchronous firing of clusters of origins that together
produce multi-replicon domains, each of which replicates at a defined time during S-phase …

Striated muscle shows an amazing ability to adapt its structural apparatus based on
contractile activity, loading conditions, fuel supply, or environmental factors. Studies with …