[HTML][HTML] The impact of spike mutated variants of SARS-CoV2 [Alpha, Beta, Gamma, Delta, and Lambda] on the efficacy of subunit recombinant vaccines

M Mohammadi, M Shayestehpour… - Brazilian Journal of …, 2021 - SciELO Brasil
Since the first described human infection with SARS-CoV-2 in December of 2019 many
subunit protein vaccines have been proposed for use in humans. Subunit vaccines use one …

COVID‐19 vaccinations: the unknowns, challenges, and hopes

K Mohamed, P Rzymski, MS Islam… - Journal of medical …, 2022 - Wiley Online Library
The entire world has been suffering from the coronavirus disease 2019 (COVID‐19)
pandemic since March 11, 2020. More than a year later, the COVID‐19 vaccination brought …

SARS-CoV-2 BA. 2.86 enters lung cells and evades neutralizing antibodies with high efficiency

L Zhang, A Kempf, I Nehlmeier, A Cossmann, A Richter… - Cell, 2024 - cell.com
Summary BA. 2.86, a recently identified descendant of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) Omicron BA. 2 sublineage, contains∼ 35 mutations …

A review on evolution of emerging SARS-CoV-2 variants based on spike glycoprotein

N Ghosh, S Nandi, I Saha - International immunopharmacology, 2022 - Elsevier
Since the inception of SARS-CoV-2 in December 2019, many variants have emerged over
time. Some of these variants have resulted in transmissibility changes of the virus and may …

Viral outbreaks detection and surveillance using wastewater-based epidemiology, viral air sampling, and machine learning techniques: A comprehensive review and …

OM Abdeldayem, AM Dabbish, MM Habashy… - Science of The Total …, 2022 - Elsevier
A viral outbreak is a global challenge that affects public health and safety. The coronavirus
disease 2019 (COVID-19) has been spreading globally, affecting millions of people …

Trivalent subunit vaccine candidates for COVID-19 and their delivery devices

OA Ortega-Rivera, MD Shin, A Chen… - Journal of the …, 2021 - ACS Publications
The COVID-19 pandemic highlights the need for platform technologies enabling rapid
development of vaccines for emerging viral diseases. The current vaccines target the SARS …

[HTML][HTML] Glycosylation of SARS-CoV-2: structural and functional insights

A Shajahan, LE Pepi, DS Rouhani, C Heiss… - Analytical and …, 2021 - Springer
The COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2). Similar to other coronaviruses, its particles are composed of four structural …

[HTML][HTML] Machine learning techniques for the prediction of B-cell and T-cell epitopes as potential vaccine targets with a specific focus on SARS-CoV-2 pathogen: A …

SNH Bukhari, A Jain, E Haq, A Mehbodniya, J Webber - Pathogens, 2022 - mdpi.com
The only part of an antigen (a protein molecule found on the surface of a pathogen) that is
composed of epitopes specific to T and B cells is recognized by the human immune system …

[HTML][HTML] Implications of testicular ACE2 and the renin–angiotensin system for SARS-CoV-2 on testis function

RC Edenfield, CA Easley IV - Nature Reviews Urology, 2022 - nature.com
Although many studies have focused on SARS-CoV-2 infection in the lungs, comparatively
little is known about the potential effects of the virus on male fertility. SARS-CoV-2 infection …

Single molecule protein segments sequencing by a plasmonic nanopore

J Zhou, Q Lan, W Li, LN Ji, K Wang, XH Xia - Nano Letters, 2023 - ACS Publications
Obtaining sequential and conformational information on proteins is vital to understand their
functions. Although the nanopore-based electrical detection can sense single molecule (SM) …