Angiogenesis, a new vessel formation from the pre-existing ones, is essential for embryonic
development, wound repair and treatment of ischemic heart and limb diseases. However …

Preeclampsia is a persistent hypertensive gestational disease characterized by high blood
pressure and proteinuria, which presents from the second trimester of pregnancy. At the …

Sepsis accounts for nearly 700 000 deaths in Europe annually and is caused by an
overwhelming host response to infection resulting in organ failure. The endothelium is an …

Reactive oxygen species (ROS) derived from NADPH oxidase (NOX) and mitochondria play
a critical role in growth factor-induced switch from a quiescent to an angiogenic phenotype …

Reactive oxygen and nitrogen species are produced in a wide range of physiological
reactions that, at low concentrations, play essential roles in living organisms. There is a …

In the vascular system, the endothelial surface layer (ESL) as the inner surface of blood
vessels affects mechanotransduction, vascular permeability, rheology, thrombogenesis, and …

Bilirubin is a standard serum biomarker of liver function. Inexplicably, it is inversely
correlated with cardiovascular disease risk. Given the role of endothelial dysfunction in …

Cardiovascular diseases (CVDs) have diverse physiopathological mechanisms with
interconnected oxidative stress and inflammation as one of the common etiologies which …

Preeclampsia is a multisystemic disorder of pregnancy that causes perinatal morbidity and
mortality. Studies published in the last decade have contributed to a better understanding of …

In cancer, angiogenesis is a critical phenomenon of nascent blood vessel development to
facilitate the oxygen and nutrient supply prerequisite for tumor progression. Therefore …