The host immune system is highly compromised in case of viral infections and relapses are
very common. The capacity of the virus to destroy the host cell by liberating its own DNA or …

Abstract Background Glucose-Regulated Protein 78 (GRP78) is a chaperone heat shock
protein that has been intensely studied in the last two decades. GRP78 is the master of the …

Zika virus (ZIKV) is spreading rapidly into regions around the world where other flaviviruses,
such as dengue virus (DENV) and West Nile virus (WNV), are endemic. Antibody-dependent …

Although Zika virus (ZIKV) was isolated approximately 70 years ago, few experimental
studies had been published prior to 2016. The recent spread of ZIKV to countries in the …

Zika virus is a member of the Flavivirus genus that had not been associated with severe
disease in humans until the recent outbreaks, when it was linked to microcephaly in …

The emergence of Zika virus (ZIKV) as a major public health threat has focused research on
understanding virus biology and developing a suite of strategies for disease intervention …

Antibodies to Zika virus (ZIKV) can be protective. To examine the antibody response in
individuals who develop high titers of anti-ZIKV antibodies, we screened cohorts in Brazil …

Virus–receptor interactions play a key regulatory role in viral host range, tissue tropism, and
viral pathogenesis. Viruses utilize elegant strategies to attach to one or multiple receptors …

Zika virus (ZIKV) infection during pregnancy has emerged as a global public health problem
because of its ability to cause severe congenital disease. Here, we developed six mouse …

Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs).
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …