[HTML][HTML] Updated insights into the T cell-mediated immune response against SARS-CoV-2: a step towards efficient and reliable vaccines

M Dhawan, AA Rabaan, MMA Fawarah, SA Almuthree… - Vaccines, 2023 - mdpi.com
The emergence of novel variants of SARS-CoV-2 and their abilities to evade the immune
response elicited through presently available vaccination makes it essential to recognize the …

[HTML][HTML] Treatment advances in sepsis and septic shock: modulating pro-and anti-inflammatory mechanisms

A Marques, C Torre, R Pinto, B Sepodes… - Journal of Clinical …, 2023 - mdpi.com
Sepsis is currently defined as a life-threatening organ dysfunction caused by a dysregulated
host response to infection, and it affects over 25 million people every year. Even more …

[HTML][HTML] Impact of Treatment with Antioxidants as an Adjuvant to Standard Therapy in Patients with Septic Shock: Analysis of the Correlation between Cytokine Storm …

I Pérez-Torres, A Aisa-Álvarez… - International Journal of …, 2023 - mdpi.com
Cellular homeostasis is lost or becomes dysfunctional during septic shock due to the
activation of the inflammatory response and the deregulation of oxidative stress. Antioxidant …

[HTML][HTML] CCR5/CXCR3 antagonist TAK-779 prevents diffuse alveolar damage of the lung in the murine model of the acute respiratory distress syndrome

AS Chernov, MV Rodionov, VA Kazakov… - Frontiers in …, 2024 - frontiersin.org
Introduction: The acute respiratory distress syndrome (ARDS), secondary to viral
pneumonitis, is one of the main causes of high mortality in patients with COVID-19 (novel …

[HTML][HTML] A Prospective Cohort Study of COVID-19: Evaluation of the Early Role of IL-1 and IL-6 Antagonists in Improving the Outcome of the Illness and Reduction in …

M Al. Kharusi, N Al Sheikh, M Alhajri, SA Al. Mandhri… - Healthcare, 2023 - mdpi.com
The COVID-19 pandemic had a profound impact on global health, economies, and social
systems. The crucial factor that determines the success of COVID-19 treatments is …

IgA is the predominant isotype of anti-β 2 glycoprotein I in patients with COVID-19

S Melayah, N Omrani, H Alouini, M Ghozzi… - Laboratory …, 2024 - academic.oup.com
Objective The aim of this research was to determine the frequency of antiphospholipid
antibodies (aPL) in patients with COVID-19. Methods The frequency and titers of …