Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies

R Kaur, M Kaur, J Singh - Cardiovascular diabetology, 2018 - Springer
The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …

Acute phase reactant serum amyloid A in inflammation and other diseases

Y Zhang, J Zhang, H Sheng, H Li, R Wang - Advances in clinical chemistry, 2019 - Elsevier
Acute-phase reactant serum amyloid A (A-SAA) plays an important role in acute and chronic
inflammation and is used in clinical laboratories as an indicator of inflammation. Although …

High-density lipoprotein anti-inflammatory capacity and incident cardiovascular events

C Jia, JLC Anderson, EG Gruppen, Y Lei, SJL Bakker… - Circulation, 2021 - Am Heart Assoc
Background: The role of high-density lipoprotein (HDL) function in cardiovascular disease
represents an important emerging concept. The present study investigated whether HDL anti …

Importance of paraoxonase 1 (PON1) as an antioxidant and antiatherogenic enzyme in the cardiovascular complications of type 2 diabetes: Genotypic and phenotypic …

Y Shokri, A Variji, M Nosrati, A Khonakdar-Tarsi… - Diabetes research and …, 2020 - Elsevier
Oxidant–antioxidant imbalance is involved in the etiology of different diseases, including
cardiovascular diseases (CVDs), liver disorders, kidney diseases, cancers and diabetes …

Steroid transport, local synthesis, and signaling within the brain: roles in neurogenesis, neuroprotection, and sexual behaviors

N Diotel, TD Charlier… - Frontiers in …, 2018 - frontiersin.org
Sex steroid hormones are synthesized from cholesterol and exert pleiotropic effects notably
in the central nervous system. Pioneering studies from Baulieu and colleagues have …

HDL functions—current status and future perspectives

Y Endo, M Fujita, K Ikewaki - Biomolecules, 2023 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of death in Western countries. A low
HDL-C is associated with the development of CVD. However, recent epidemiology studies …

High-density lipoprotein alterations in type 2 diabetes and obesity

D Denimal, S Monier, B Bouillet, B Vergès, L Duvillard - Metabolites, 2023 - mdpi.com
Alterations affecting high-density lipoproteins (HDLs) are one of the various abnormalities
observed in dyslipidemia in type 2 diabetes mellitus (T2DM) and obesity. Kinetic studies …

ApoA-I and diabetes

TW King, BJ Cochran, KA Rye - Arteriosclerosis, Thrombosis, and …, 2023 - Am Heart Assoc
ApoA-I—the main apolipoprotein constituent of the HDL (high-density lipoprotein) fraction of
human plasma—is of therapeutic interest because it has several cardioprotective functions …

HDL dysfunctionality: clinical relevance of quality rather than quantity

A Bonizzi, G Piuri, F Corsi, R Cazzola, S Mazzucchelli - Biomedicines, 2021 - mdpi.com
High-density lipoproteins (HDLs) represent a class of lipoproteins very heterogeneous in
structure, composition, and biological functions, which carry out reverse cholesterol …

Antioxidant and anti-inflammatory functions of high-density lipoprotein in type 1 and type 2 diabetes

D Denimal - Antioxidants, 2023 - mdpi.com
(1) Background: high-density lipoproteins (HDLs) exhibit antioxidant and anti-inflammatory
properties that play an important role in preventing the development of atherosclerotic …