The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

Natural and experimental SARS-CoV-2 infection in domestic and wild animals

DA Meekins, NN Gaudreault, JA Richt - Viruses, 2021 - mdpi.com
SARS-CoV-2 is the etiological agent responsible for the ongoing COVID-19 pandemic,
which continues to spread with devastating effects on global health and socioeconomics …

SARS-CoV-2 induces lymphocytopenia by promoting inflammation and decimates secondary lymphoid organs

Q Xiang, Z Feng, B Diao, C Tu, Q Qiao, H Yang… - Frontiers in …, 2021 - frontiersin.org
While lymphocytopenia is a common characteristic of coronavirus disease 2019 (COVID-
19), the mechanisms responsible for this lymphocyte depletion are unclear. Here, we …

[HTML][HTML] The role of CD4+ FoxP3+ regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment

Y Wang, J Zheng, MS Islam, Y Yang… - International journal of …, 2021 - ncbi.nlm.nih.gov
The severe cases of Coronavirus Disease 2019 (COVID-19) frequently exhibit excessive
inflammatory responses, acute respiratory distress syndrome (ARDS), coagulopathy, and …

Animal models for SARS-CoV-2

CY Lee, AC Lowen - Current opinion in virology, 2021 - Elsevier
Since its first detection in December 2019, severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) has rapidly spread worldwide, resulting in over 79.2 million documented …

Zoonotic and reverse zoonotic transmissibility of SARS-CoV-2

IV Goraichuk, V Arefiev, BT Stegniy, AP Gerilovych - Virus research, 2021 - Elsevier
Abstract The Coronavirus Disease 2019 (COVID-19) is the first known pandemic caused by
a coronavirus. Its causative agent, severe acute respiratory syndrome coronavirus 2 (SARS …

Regulatory T cells (Tregs) and COVID-19: unveiling the mechanisms, and therapeutic potentialities with a special focus on long COVID

M Dhawan, AA Rabaan, S Alwarthan, M Alhajri… - Vaccines, 2023 - mdpi.com
The COVID-19 pandemic has caused havoc all around the world. The causative agent of
COVID-19 is the novel form of the coronavirus (CoV) named SARS-CoV-2, which results in …

Development of a coronavirus disease 2019 nonhuman primate model using airborne exposure

SC Johnston, KM Ricks, A Jay, JL Raymond, F Rossi… - PloS one, 2021 - journals.plos.org
Airborne transmission is predicted to be a prevalent route of human exposure with SARS-
CoV-2. Aside from African green monkeys, nonhuman primate models that replicate …

SARS CoV-2 infections in animals, two years into the pandemic

S Frazzini, M Amadori, L Turin, F Riva - Archives of Virology, 2022 - Springer
In December 2019, several cases of pneumonia caused by a novel coronavirus, later
identified as SARS-CoV-2, were detected in the Chinese city of Wuhan. Due to its rapid …

Differential susceptibility of SARS‐CoV‐2 in animals: Evidence of ACE2 host receptor distribution in companion animals, livestock and wildlife by …

FZX Lean, A Núñez, S Spiro… - Transboundary and …, 2022 - Wiley Online Library
Abstract Angiotensin converting enzyme 2 (ACE2) is a host cell membrane protein (receptor)
that mediates the binding of coronavirus, most notably SARS coronaviruses in the …