Identification and classification of papain-like cysteine proteinases

F Ozhelvaci, K Steczkiewicz - Journal of Biological Chemistry, 2023 - ASBMB
Papain-like cysteine peptidases form a big and highly diverse superfamily of proteins
involved in many important biological functions, such as protein turnover, deubiquitination …

Research progress in porcine reproductive and respiratory syndrome virus–host protein interactions

H Zhang, H Sha, L Qin, N Wang, W Kong, L Huang… - Animals, 2022 - mdpi.com
Simple Summary PRRSV–host protein interactions are of great significance in finding new
antiviral targets. We summarize the effects of all the PRRSV structural and nonstructural …

[HTML][HTML] Nonstructural protein 1α subunit-based inhibition of NF-κB activation and suppression of interferon-β production by porcine reproductive and respiratory …

C Song, P Krell, D Yoo - Virology, 2010 - Elsevier
Induction of type I interferon (IFN-α/β) is an early antiviral response of the host, and porcine
reproductive and respiratory syndrome virus (PRRSV) has been reported to downregulate …

The function of the PRRSV–host interactions and their effects on viral replication and propagation in antiviral strategies

J Ma, L Ma, M Yang, W Wu, W Feng, Z Chen - Vaccines, 2021 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV) affects the global swine
industry and causes disastrous economic losses each year. The genome of PRRSV is an …

Identification of porcine reproductive and respiratory syndrome virus ORF1a-encoded non-structural proteins in virus-infected cells

Y Li, A Tas, EJ Snijder, Y Fang - Journal of general …, 2012 - microbiologyresearch.org
The porcine reproductive and respiratory syndrome virus (PRRSV) replicase gene consists
of two large ORFs, ORF1a and ORF1b, the latter of which is expressed by ribosomal …

Immunological features of the non-structural proteins of porcine reproductive and respiratory syndrome virus

E Rascón-Castelo, A Burgara-Estrella, E Mateu… - Viruses, 2015 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV) is currently one of the most
important viruses affecting the swine industry worldwide. Despite the large number of papers …

Proteolytic processing of the porcine reproductive and respiratory syndrome virus replicase

Y Li, A Tas, Z Sun, EJ Snijder, Y Fang - Virus research, 2015 - Elsevier
The porcine reproductive and respiratory syndrome virus (PRRSV) replicase polyproteins
pp1a and pp1ab are proteolytically processed by four proteases encoded in ORF1a. In this …

[HTML][HTML] Porcine reproductive and respiratory syndrome virus non-structural protein 1 suppresses tumor necrosis factor-alpha promoter activation by inhibiting NF-κB …

S Subramaniam, B Kwon, LK Beura, CA Kuszynski… - Virology, 2010 - Elsevier
The objective of this study was to identify porcine reproductive and respiratory syndrome
virus (PRRSV)-encoded proteins that are responsible for the inhibition of TNF-α expression …

Overview: replication of porcine reproductive and respiratory syndrome virus

SI Yun, YM Lee - Journal of microbiology, 2013 - Springer
Porcine reproductive and respiratory syndrome virus (PRRSV), an arterivirus that causes
significant losses in the pig industry, is one of the most important animal pathogens of global …

Engineering the PRRS virus genome: Updates and perspectives

M Han, D Yoo - Veterinary microbiology, 2014 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) is endemic in most pig
producing countries worldwide and causes enormous economic losses to the pork industry …