Ingestion of a high‐fat diet composed mainly of the saturated fatty acid, palmitic (PA), and
the unsaturated fatty acid, oleic (OA), stimulates transcription in the brain of the opioid …

Gliobastoma (GB), the most common adult brain tumor, infiltrates normal brain area
rendering impossible the complete surgical resection, resulting in a poor median survival …

Our previous studies showed that propane-2-sulfonic acid octadec-9-enyl-amide (N15), a
novel peroxisome proliferator-activated receptors α and γ (PPARα/γ) dual agonist, protected …

Activation of peroxisome proliferator-activated receptor alpha (PPARα) has been reported to
modulate cell proliferation, migration, and differentiation in astrocytes. In this study, we used …

Background: Differentiating oligodendrocyte precursor cells (OPCs) into oligodendrocytes
could be improved by inhibiting signaling pathways such as Wnt and Notch. 9-cis-retinoic …

Insulin resistance (IR) is a risk factor for metabolic disorders and neurodegeneration.
Peroxisome proliferator‐activated receptor (PPAR) agonists have been proven to mitigate …

This study demonstrates that adipose‐derived stem cells from debrided skin (dsASCs) of
burn patients can be isolated in sufficient quantities and differentiated into cytokeratin …

Gestational exposure to a fat-rich diet, while elevating maternal circulating fatty acids,
increases in the offspring's hypothalamus and amygdala the proliferation and density of …

目的探讨过氧化物酶体增殖物激活受体γ (PPARγ) 对脑内胰岛素受体底物-4 (IRS-4)
基因表达的影响. 方法体外实验采用原代培养1 周的大鼠皮层神经元, 用10μmol/LPPARγ …

In recent years, beneficial effects of various ligands of three peroxisome-proliferatoractivated
receptor (PPAR) isoforms (α, β, γ) have been reported in neurodegenerative diseases …